Efficacy of analgesia promoted by lidocaine and articaine in third molar extraction surgery. A split-mouth, randomized, controlled trial.

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-06-01 Epub Date: 2024-02-15 DOI:10.1007/s10006-024-01223-4

Samara de Souza Santos, Mariana Silva Bonatto, Pedro Gomes Junqueira Mendes, Ana Vitória Borges Martins, Davisson Alves Pereira, Guilherme José Pimentel Lopes de Oliveira

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引用次数: 0

Abstract

Purpose: The aim of this study was to compare the analgesic efficacy of 4% articaine associated with epinephrine (1:100,000), and 2% lidocaine associated with epinephrine (1:100,000) in third molar extraction surgery.

Methods: Sixty patients who underwent surgeries to extract upper and lower third molars were included in this split-mouth, double-blind, randomized, controlled trial. The groups in this study were divided according to the anesthetic solution used to provide local anesthesia during extraction of upper and lower third molars: (1) 4% articaine associated with epinephrine (1:100,000); (2) 2% lidocaine associated with epinephrine (1:100,000). The time to the beginning and end of the sensation of analgesia, pain sensation according to the VAS scale, and number of anesthetic tubes necessary for supplementation were analyzed.

Results: It was found that the onset time for analgesia was shorter on the side anesthetized with articaine compared to the side anesthetized with lidocaine (122.1 ± 52.90 s vs. 144.5 ± 68.85 s) (p < 0.05). In addition, the number of tubes used for anesthetic supplementation was also reduced on the articaine side compared to the lidocaine side (0.26 ± 0.48 vs. 0.50 ± 0.75) (p < 0.05). There were no differences between the anesthetic solutions in the other evaluated parameters.

Conclusion: It can be concluded that the use of 4% articaine associated with epinephrine (1:100,000) reduced the time of onset of analgesia and the necessity for anesthetic supplementation in third molar extraction surgeries compared to the use of 2% lidocaine associated with epinephrine (1:100,000).

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利多卡因和阿替卡因在第三磨牙拔除手术中的镇痛效果。分口随机对照试验。

目的：本研究旨在比较 4% 阿替卡因与肾上腺素（1:100,000）和 2% 利多卡因与肾上腺素（1:100,000）在第三磨牙拔除手术中的镇痛效果：这项分口、双盲、随机对照试验共纳入了 60 名接受拔除上下第三磨牙手术的患者。根据拔除上、下第三磨牙时使用的局部麻醉溶液不同，该研究分为两组：(1) 4%阿替卡因与肾上腺素（1:100,000）；(2) 2%利多卡因与肾上腺素（1:100,000）。分析了镇痛感觉开始和结束的时间、VAS量表显示的疼痛感觉以及补充麻醉剂所需的麻醉管数量：结果发现，与使用利多卡因麻醉的一侧相比，使用阿替卡因麻醉的一侧的镇痛开始时间更短（122.1 ± 52.90 秒 vs. 144.5 ± 68.85 秒）（p 结论：使用利多卡因麻醉的一侧的镇痛开始时间更短（122.1 ± 52.90 秒 vs. 144.5 ± 68.85 秒）：与使用 2% 利多卡因和肾上腺素（1:100,000）相比，使用 4% 阿替卡因和肾上腺素（1:100,000）可缩短第三磨牙拔除手术的镇痛起效时间，并减少补充麻醉剂的必要性。

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来源期刊

Oral and Maxillofacial Surgery-Heidelberg DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.20

自引率

5.60%

发文量

118

期刊介绍： Oral & Maxillofacial Surgery founded as Mund-, Kiefer- und Gesichtschirurgie is a peer-reviewed online journal. It is designed for clinicians as well as researchers.The quarterly journal offers comprehensive coverage of new techniques, important developments and innovative ideas in oral and maxillofacial surgery and interdisciplinary aspects of cranial, facial and oral diseases and their management. The journal publishes papers of the highest scientific merit and widest possible scope on work in oral and maxillofacial surgery as well as supporting specialties. Practice-oriented articles help improve the methods used in oral and maxillofacial surgery.Every aspect of oral and maxillofacial surgery is fully covered through a range of invited review articles, clinical and research articles, technical notes, abstracts, and case reports. Specific topics are: aesthetic facial surgery, clinical pathology, computer-assisted surgery, congenital and craniofacial deformities, dentoalveolar surgery, head and neck oncology, implant dentistry, oral medicine, orthognathic surgery, reconstructive surgery, skull base surgery, TMJ and trauma.Time-limited reviewing and electronic processing allow to publish articles as fast as possible. Accepted articles are rapidly accessible online.Clinical studies submitted for publication have to include a declaration that they have been approved by an ethical committee according to the World Medical Association Declaration of Helsinki 1964 (last amendment during the 52nd World Medical Association General Assembly, Edinburgh, Scotland, October 2000). Experimental animal studies have to be carried out according to the principles of laboratory animal care (NIH publication No 86-23, revised 1985).