The Association Between Oral Mucosal Lesions and Oral Health-Related Quality of Life Using the Validated Indonesian Version of OHIP-14 Among People Living with HIV/AIDS.

IF 1.5 Q4 INFECTIOUS DISEASES

HIV AIDS-Research and Palliative Care Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI:10.2147/HIV.S452154

Irna Sufiawati, Tuty Amalia, Tenny Setiani Dewi, Rudi Wisaksana

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Abstract

Background: Oral mucosal lesions in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients, posing a concern for healthcare professionals, impact their oral health-related quality of life (OHRQoL). This study aimed to evaluate the association between oral mucosal lesions and OHRQoL as measured by the validated Indonesian version of the oral health impact profile-14 questionnaire (OHIP-14) among people living with HIV/AIDS (PLWHA).

Methods: A cross-sectional study was conducted at the Central Referral Hospital in West Java, Indonesia. The validity of OHIP-14 was evaluated in 30 PLWHA using inter-item corrected correlation, while reliability was assessed through Cronbach's alpha and kappa coefficient agreement. Subsequently, a consecutive sample of 110 PLWHA self-completed the validated Indonesian version of OHIP-14 and underwent an oral examination. The association between oral mucosal lesions and OHRQoL was analyzed using the chi-squared test.

Results: The validity test of the OHIP-14 questionnaire produced a r_count > 0.189, meaning that all question items were valid and could be used to describe OHRQoL. The reliability test of the OHIP-14 questionnaire produced a Cronbach's alpha value of 0.960 (> 0.7), which means that overall, the OHIP-14 questionnaire is reliable and feasible to be used to assess OHRQoL. Among the 110 enrolled participants, 61.8% were female and 38.2% were male, with the mean age 23.5 years old, the majority of them (59.1%) had been taking antiretrovirals (ARV), and (81.5%) had good QoL. There was a statistically significant relationship between oral lesions and quality of life (p<0.05), particularly acute pseudomembranous candidiasis, angular cheilitis, recurrent intraoral herpes, and Stevens-Johnson syndrome.

Conclusion: This study indicated a significant association between oral mucosal lesions and OHRQoL in PLWHA. The successfully validated Indonesian version of the OHIP-14 questionnaire serves as a reliable and effective tool for assessing OHRQoL among PLWHA.

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使用经过验证的印尼版 OHIP-14 研究艾滋病毒/艾滋病感染者口腔黏膜病变与口腔健康相关生活质量之间的关系。

背景：人类免疫缺陷病毒（HIV）和获得性免疫缺陷综合征（AIDS）患者的口腔黏膜病变会影响他们与口腔健康相关的生活质量（OHRQoL），引起医护人员的关注。本研究旨在评估口腔黏膜病变与口腔健康影响档案-14 问卷（OHIP-14）印尼验证版在艾滋病病毒感染者/艾滋病患者（PLWHA）中测量的口腔健康相关生活质量（OHRQoL）之间的关系：方法：在印度尼西亚西爪哇的中央转诊医院进行了一项横断面研究。方法：在印度尼西亚西爪哇的中央转诊医院进行了一项横断面研究，使用项目间校正相关性对 30 名艾滋病感染者进行了 OHIP-14 的有效性评估，并通过 Cronbach's alpha 和 kappa 系数一致性对其可靠性进行了评估。随后，110 名连续抽样的 PLWHA 自行填写了经过验证的印尼版 OHIP-14，并接受了口腔检查。采用卡方检验分析了口腔黏膜病变与 OHRQoL 之间的关联：结果：OHIP-14问卷的有效性测试结果为rcount>0.189，这意味着所有问题项目均有效，可用于描述OHRQoL。OHIP-14问卷的信度测试结果显示，Cronbach's alpha值为0.960（大于0.7），这意味着总体而言，OHIP-14问卷是可靠的，可以用来评估OHRQoL。在 110 名登记的参与者中，61.8% 为女性，38.2% 为男性，平均年龄为 23.5 岁，其中大多数人（59.1%）一直在服用抗逆转录病毒药物（ARV），81.5% 的人具有良好的 QoL。口腔病变与生活质量之间存在统计学意义上的显著关系（p 结论：这项研究表明，在 PLWHA 患者中，口腔黏膜病变与 OHRQoL 之间存在明显关联。成功验证的印尼版 OHIP-14 问卷是评估 PLWHA 口腔健康和生活质量的可靠而有效的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HIV AIDS-Research and Palliative Care INFECTIOUS DISEASES-

CiteScore

3.00

自引率

6.70%

发文量

审稿时长

16 weeks

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