PHYTOCHEMICAL STUDY OF BACCHARIS DRACUNCULIFOLIA (ASTERACEAE) WITH ANTIOXIDANT POTENTIAL FOR THE DEVELOPMENT OF PHYTOCOSMETICS FORMULATION

Juliana Maria Rocha e Silva Crespo, Pamella Teixeira Lazzari, Rondinelli De Carvalho Ladeira, Marcelo Soares Crespo, Sthepano Picanço Damian Resende
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Abstract

This study addressed the development of a phytocosmetic with antioxidant appeal, using the extract of Baccharis dracunculifolia (Asteraceae) with therapeutic potential as the active ingredient. The research involved the phytochemical analysis of the plant, highlighting the presence of compounds such as alkaloids, flavonoids, and tannins, indicative of antioxidant activity. Baccharis dracunculifolia, known as “alecrim do campo,” was collected in the rural area of Muriaé, MG, and subjected to different extraction techniques to obtain hydroalcoholic and glycolic extracts. Phytochemical screening revealed the presence of phenols, tannins, saponins, and other compounds, crucial for the desired activity. Based on these results, a phytocosmetic gel with a low concentration of fatty components was formulated, aiming for efficacy and safety. The stability of the product was assessed under various conditions, and physicochemical parameters, such as pH and viscosity, were monitored. The phyto-cosmetic gel demonstrated stability throughout the study, maintaining its organoleptic and physicochemical characteristics. The final product composition included 2% of alcoholic extract of Baccharis dracunculifolia. This study contributes to the research on antioxidant phytocosmetics, highlighting the therapeutic potential of Baccharis dracunculifolia, but additional “in vivo” tests are required to validate its safety and efficacy in users.
为开发植物化妆品配方而对具有抗氧化潜力的赤桉树(菊科)进行的植物化学研究
本研究利用具有治疗潜力的龙胆草(菊科)提取物作为活性成分,开发了一种具有抗氧化功效的植物化妆品。研究涉及对该植物的植物化学分析,突出了生物碱、黄酮类和单宁酸等化合物的存在,这些化合物具有抗氧化活性。Baccharis dracunculifolia 被称为 "alecrim do campo",采集于 MG 省 Muriaé 的农村地区,通过不同的提取技术获得水醇提取物和乙醇提取物。植物化学筛选显示,其中含有酚类、单宁酸、皂苷和其他对所需活性至关重要的化合物。基于这些结果,我们配制出了一种脂肪成分浓度较低的植物美容凝胶,旨在确保其功效和安全性。在各种条件下对产品的稳定性进行了评估,并对 pH 值和粘度等理化参数进行了监测。植物化妆品凝胶在整个研究过程中表现出稳定性,保持了其感官和理化特性。最终产品的成分中含有 2% 的龙须菜酒精提取物。这项研究为抗氧化植物化妆品的研究做出了贡献,凸显了龙胆草的治疗潜力,但还需要更多的 "体内 "测试来验证其对使用者的安全性和有效性。
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