Effectiveness of Non-pharmacological Interventions for Adolescents With Type 1 Diabetes in the Last Five Years: A Systematic Review and Meta-analysis

IF 2.1 3区医学 Q2 NURSING

Asian Nursing Research Pub Date : 2024-02-01 DOI:10.1016/j.anr.2024.01.008

DaeEun Lee , Haejung Lee , YoonYoung Shin , Gaeun Park

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引用次数: 0

Abstract

Purpose

Evidence on non-pharmacological interventions for adolescents with type 1 diabetes is unclear. This review aimed to evaluate the effectiveness of non-pharmacological intervention in adolescents with type 1 diabetes.

Methods

We conducted a search on databases from November 11 to 19, 2022, for randomized controlled trials for the effects of non-pharmacological intervention in adolescents with type 1 diabetes. To identify recent research trends, we included studies published from 2017 to November 2022. The risk of bias was assessed using the Cochrane risk-of-bias tool 2.0. To estimate the effect size, a meta-analysis was performed using RevMan 5.4 program and R Studio.

Results

A total of 45 studies were included in the systematic review. Among those, 30 studies were included in the meta-analysis. Non-pharmacological interventions were significantly effective in improving Glycated hemoglobin (HbA1c) (standardized mean difference [SMD] = −0.26, 95% confidence interval [CI]: −0.42, −0.09), quality of life (SMD = 0.44, 95% CI: 0.13 to 0.76), and anxiety (SMD = −0.91, 95% CI: −1.26, −0.56). Subgroup analysis showed that duration of intervention was not a covariate related to HbA1c levels.

Conclusions

Non-pharmacological interventions have shown effectiveness in improving the HbA1c, quality of life, and anxiety in adolescents with type 1 diabetes. Future studies with more rigorous methodology are needed to confirm and strengthen the validity of these findings. Additionally, attention to changes in the lipid profile and self-care motivation among adolescents with type 1 diabetes is warranted.

Trial registration number

Prospective Register of Systematic Reviews (CRD42022382190).

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过去五年对 1 型糖尿病青少年进行非药物干预的效果：系统回顾和荟萃分析

目的有关对 1 型糖尿病青少年患者进行非药物干预的证据尚不明确。本综述旨在评估非药物干预对1型糖尿病青少年患者的有效性。方法我们从2022年11月11日至19日在数据库中检索了有关非药物干预对1型糖尿病青少年患者影响的随机对照试验。为了确定近期的研究趋势，我们纳入了2017年至2022年11月发表的研究。偏倚风险采用 Cochrane Risk of Bias Tool 2.0 进行评估。为了估计效应大小，我们使用 RevMan 5.4 程序和 R Studio 进行了荟萃分析。其中，30 项研究被纳入荟萃分析。非药物干预对改善 HbA1c（SMD=-0.26，95% CI：-0.42，-0.09）、生活质量（SMD=0.44，95% CI：0.13 至 0.76）、焦虑（SMD=-0.91，95% CI：-1.26，-0.56）和血糖（SMD=-1.62，95% CI：-2.22，-1.01）有显著效果。亚组分析显示，干预持续时间不是与 HbA1c 水平相关的协变量。结论非药物干预在改善 1 型糖尿病青少年患者的 HbA1c、生活质量、焦虑和血糖方面显示出有效性。今后需要采用更严格的方法进行研究，以证实和加强这些研究结果的有效性。此外，还需要关注 1 型糖尿病青少年血脂状况和自我护理动机的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Nursing Research NURSING-

CiteScore

4.20

自引率

4.50%

发文量

审稿时长

45 days

期刊介绍： Asian Nursing Research is the official peer-reviewed research journal of the Korean Society of Nursing Science, and is devoted to publication of a wide range of research that will contribute to the body of nursing science and inform the practice of nursing, nursing education, administration, and history, on health issues relevant to nursing, and on the testing of research findings in practice.