Erik Wu , Joseph Reznicek , Anjana V. Yeldandi , Jyoti D. Patel , David D. Odell
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引用次数: 0
Abstract
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Primary pulmonary lymphoepithelial carcinoma (LEC) is an extremely rare form of lung cancer that is most often associated with Epstein Barr virus and affects a different patient population than other lung cancer subtypes.
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There is no consensus on treatment strategy for primary pulmonary LEC due to its rarity, and most locally advanced disease is managed with resection followed by adjuvant chemotherapy.
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This case marks the first documented occurrence of primary pulmonary LEC treated with neoadjuvant chemotherapy and PD1 checkpoint immunotherapy, demonstrating significant radiological response, followed by successful complete resection.
期刊介绍:
Clinical Lung Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of lung cancer. Clinical Lung Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of lung cancer. The main emphasis is on recent scientific developments in all areas related to lung cancer. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.