Late Pulmonary Autograft Dilation: Can We Make a Good Operation Great? The Supported Ross

Q2 Medicine
Michael E. Mitchell MD , Ronald K. Woods MD, PhD , Tracy R. Geoffrion MD, MPH , Mami Sow MD
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引用次数: 0

Abstract

The Ross procedure is an excellent option for aortic valve replacement resulting in outstanding hemodynamic performance and the ability to avoid systemic anticoagulation. The long-term durability of the autograft is generally good but concerns for later aortic root dilation with ensuing neoaortic insufficiency have prompted efforts to stabilize the autograft, root, sinuses and Sino-tubular junction in order to delay or entirely avoid late reinterventions on the neoaortic root. We have employed an inclusion technique, supporting the Auto-graft in a Terumo Gelweave™ Valsalva graft. We performed a retrospective study of all 129 patients undergoing the Ross procedure from 1992 to 2019 at Children's Wisconsin. Fifty-one underwent the supported Ross (SR) and 78 underwent unsupported Ross (UR). Structured clinical data was collected and echocardiograms were reviewed. Median follow-up was 4.9 years (up to 22.6 years) for UR patients and 3.6 years (up to 11.4 years) for SR patients. In order to provide a fair comparison, we sub -analyzed patients aged 10 to 18 years who underwent the Ross procedure, 16 who underwent the UR and 18 patients who underwent the SR. Change in aortic annulus diameter (P = 0.002), aortic sinus diameter (P = 0.001) change in left ventricular function (P = 0.039) and change in aortic insufficiency (P = 0.008) were all worse in UR. The SR is simple, reproducible, and predictable. It seems to prevent change in annulus diameter, sinus diameter and to reduce late neoaortic insufficiency. Longer follow-up with a larger group of patients is required to draw definitive conclusions.

肺自体移植晚期扩张:我们能让好手术变得更好吗?得到支持的罗斯
罗斯手术是主动脉瓣置换术的绝佳选择,具有出色的血流动力学表现,并能避免全身抗凝。自体移植物的长期耐久性通常很好,但人们担心日后主动脉根部扩张会导致新主动脉瓣关闭不全,这促使人们努力稳定自体移植物、根部、窦部和中管交界处,以延迟或完全避免对新主动脉根部的后期再干预。我们采用了一种包容技术,在 Terumo Gelweave™ Valsalva 移植物中支撑自体移植物。我们对 1992 年至 2019 年期间在威斯康星州儿童医院接受罗斯手术的所有 129 名患者进行了回顾性研究。其中 51 人接受了有支撑 Ross(SR)手术,78 人接受了无支撑 Ross(UR)手术。研究人员收集了结构化临床数据,并对超声心动图进行了审查。UR患者的中位随访时间为4.9年(最长22.6年),SR患者的中位随访时间为3.6年(最长11.4年)。为了进行公平比较,我们对接受 Ross 手术的 10 至 18 岁患者、接受 UR 手术的 16 名患者和接受 SR 手术的 18 名患者进行了子分析。主动脉瓣环直径的变化(P = 0.002)、主动脉窦直径的变化(P = 0.001)、左室功能的变化(P = 0.039)和主动脉瓣关闭不全的变化(P = 0.008)在 Ross 术中都较差。SR 简单、可重复、可预测。它似乎可以防止瓣环直径和窦道直径的变化,并减少晚期新主动脉瓣关闭不全。要得出明确的结论,还需要对更多患者进行长期随访。
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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
7
期刊介绍: The Pediatric Cardiac Surgery Annual is a companion to Seminars in Thoracic and Cardiovascular Surgery . Together with the Seminars, the Annual provides complete coverage of the specialty by focusing on important developments in pediatric cardiac surgery. Each annual volume has an expert guest editor who invites prominent surgeons to review the areas of greatest change in pediatric cardiac surgery during the year. Topics include 1) Complete Atrioventricular Canal; 2) New Concepts of Cardiac Anatomy and Function -- The Helical Heart; 3) Valve Reconstruction (Replacement) in Congenital Heart Disease; 4) Evolving Developments in Congenital Heart Surgery.
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