Incidence and Risk Factors of Morbidity and Mortality in Emergency Laparotomy

Hanaa Taha, S. Arif, Ayad Mohammed
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Abstract

Background: The indications for emergency laparotomy are many, depending on different pathological causes, organs involved, and preoperative management. All these factors limit the time to optimize the comorbidities that may affect the outcome of surgery in terms of morbidity and mortality. Objectives: We aimed to detect the different predicting factors for morbidity and mortality after emergency laparotomies. Materials and methods: This prospective cohort study was conducted on 100 patients who were subjected to an emergency laparotomy. The demographic and clinical characteristics of the enrolled participants were registered. The study was carried out at Duhok Emergency Teaching Hospital from February 2022 to January 2023. Patients were followed for 30 days after surgery. Results: The mean age of the patients was 39.26 years ± 19.53, and males constituted 2/3 rd of the cases. The non-traumatic causes comprised the majority of cases. Patients with acute abdomen and intestinal obstruction comprised 74% of the cases. The commonest imaging finding was intra-abdominal collections (35%). The commonest operative finding was perforated gastric or duodenal ulcer (19%). Morbidity was reported in 69 patients. These included wound infection, anastomotic leakage, bleeding, deep venous thrombosis, and burst abdomen. There was a significant association (P-value < 0.05) between the morbidity and the age of the patient (OR: 1.5), body weight (OR: 1.9), associated comorbidities (OR: 1.2), operative time (OR: 1.76), performance of bowel anastomosis (OR: 5.5), and admission to the intensive care unit (ICU) (OR: 2.79). Mortality was reported in 9 patients, and there was a significant association (P-value < 0.05) with anastomotic leakage (OR: 4.27), need for anti-coagulation (OR: 23.65), and admission to the ICU (OR: 16.36). Conclusion: Emergency laparotomy is associated with high incidences of morbidity and mortality. The patient’s age, body weight, associated comorbidities, operative time, performance of bowel anastomosis, and admission to the ICU might be risk factors for morbidity. High mortality might be due to anastomotic leakage, the requirement of anticoagulation, and ICU admission.
急诊腹腔手术中发病率和死亡率的发生率和风险因素
背景:急诊开腹手术的适应症很多,取决于不同的病因、涉及的器官和术前处理。所有这些因素都限制了优化合并症的时间,而合并症可能会影响手术的发病率和死亡率。研究目的我们旨在检测急诊开腹手术后发病率和死亡率的不同预测因素。材料和方法:这项前瞻性队列研究的对象是100名接受急诊开腹手术的患者。登记了入选者的人口统计学和临床特征。研究于 2022 年 2 月至 2023 年 1 月在杜霍克急诊教学医院进行。术后对患者进行了 30 天的随访。研究结果患者的平均年龄为 39.26 岁 ± 19.53 岁,男性占病例总数的三分之二。非创伤性病因占大多数。急腹症和肠梗阻患者占 74%。最常见的影像学检查结果是腹腔内积液(35%)。最常见的手术发现是胃或十二指肠溃疡穿孔(19%)。69名患者报告了发病率。其中包括伤口感染、吻合口渗漏、出血、深静脉血栓和腹部破裂。发病率与患者年龄(OR:1.5)、体重(OR:1.9)、相关并发症(OR:1.2)、手术时间(OR:1.76)、肠吻合术(OR:5.5)和入住重症监护室(ICU)(OR:2.79)之间存在显著相关性(P 值小于 0.05)。据报告,9 名患者出现死亡,与吻合口漏(OR:4.27)、需要抗凝(OR:23.65)和入住重症监护室(OR:16.36)有显著关联(P 值<0.05)。结论急诊开腹手术的发病率和死亡率都很高。患者的年龄、体重、相关并发症、手术时间、肠吻合术的实施以及入住重症监护室可能是发病率的风险因素。死亡率高的原因可能是吻合口漏、需要抗凝以及入住重症监护室。
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