Resistance profile of pathogenic strains isolated from community acquired infection at the Protestant Hospital of Ngaoundere (Cameroon)

B. Talom, Destin Haiwe Dahara, Francky Steve Sohanang Nodem, Cyrille Léonel Tchuenté Djoko, Nicodème Yangai Sodea, Ermoult Xavier Damoulaye, Rosine Carmène Diffo Heymata
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Abstract

Worldwide data show that there is increasing resistance among infection bacteria to conventional drugs. The present study aimed at determining data on susceptibility of bacteria isolated from patient for community acquired infection in Protestant Hospital of Ngaoundere against prescribed antibiotics in case of infections by these bacteria. Bacteriological profile of collected samples (stool, urine, cervico-vaginal and urethral secretion, blood) was carry out by standard method. Antibiotic susceptibility was done by the agar disk diffusion method. A total of 120 samples were collected. Among 46 samples was positive for bacterial infections germs (38% of prevalence). Stomach pain represents the most frequent complaint of patients (33.1%). Enterobacteriaceae were the most isolated (70%) followed by Neisseria gonorrhoeae (15%). About 73.0% of Enterobacteriaceae identified were resistant to ticarcillin while 80% of N. gonorrhoeae to ampicillin. Some of the isolates were resistant to ticarpen (73%), oxacillin (71%) and tobramycin (57%) which are more frequently prescribed and indicates that increased consumption of a particular antibiotic leads to acquisition of resistance. Enterobacteriaceae were predominant bacterial isolated and it is necessary to continue monitoring the consumption of antibiotics to ensure good management of infections.
从恩冈代雷新教医院(喀麦隆)社区感染中分离出的病原菌耐药性概况
全球数据显示,感染细菌对常规药物的耐药性越来越强。本研究旨在确定恩冈代雷新教医院从社区感染患者身上分离出的细菌对处方抗生素的敏感性数据。采用标准方法对采集的样本(粪便、尿液、宫颈阴道和尿道分泌物、血液)进行细菌学分析。抗生素敏感性采用琼脂盘扩散法检测。共收集了 120 份样本。在 46 份样本中,细菌感染病菌呈阳性(占流行率的 38%)。胃痛是患者最常见的主诉(33.1%)。分离出的细菌以肠杆菌科细菌最多(70%),其次是淋病奈瑟菌(15%)。约 73.0% 的肠杆菌科细菌对替卡西林有抗药性,而 80% 的淋病奈瑟菌对氨苄西林有抗药性。一些分离菌株对替卡西林(73%)、奥沙西林(71%)和妥布霉素(57%)产生耐药性,而这些抗生素的处方频率较高,这表明使用某种抗生素的次数增加会导致耐药性的产生。肠杆菌科细菌是主要的分离细菌,因此有必要继续监测抗生素的使用情况,以确保对感染进行良好管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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