Clinical case of benralizumab use in severe eosinophilic bronchial asthma in the Republic of Dagestan

Seypula Sh. Ахмедханов, Saida G. Gadzhiyeva, Albina T. Beybalayeva, Z. Saidova
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Abstract

This article presents the results of the examination, observation, and treatment of a patient with severe persistent bronchial asthma with an eosinophilic phenotype who received benralizumab (Fazenra) in a complex treatment. Benralizumab is indicated for patients with severe bronchial asthma with an eosinophilic phenotype in adult patients as an additional maintenance therapy, in which the use of glucocorticosteroids does not achieve control over the symptoms of the disease. With complex therapy, the inclusion of benralizumab led to positive dynamics of both clinical symptoms and indicators of respiratory function, which allowed us to reduce the volume of therapy with corticosteroids and achieve disease control. The above case is of interest to both pulmonologists and therapists.
达吉斯坦共和国严重嗜酸性粒细胞支气管哮喘患者使用苯拉利珠单抗的临床病例
本文介绍了一名嗜酸性粒细胞表型的重症持续性支气管哮喘患者接受苯拉利珠单抗(Fazenra)复合治疗后的检查、观察和治疗结果。Benralizumab 适用于成年嗜酸性粒细胞表型的重症支气管哮喘患者,在使用糖皮质激素无法控制疾病症状的情况下,可作为一种额外的维持疗法。在复合疗法中,加入苯拉利珠单抗后,临床症状和呼吸功能指标都出现了积极的动态变化,这使我们能够减少糖皮质激素的治疗量,实现疾病控制。肺科医生和治疗师都对上述病例很感兴趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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