Frontal Sinus Fractures and Traumatic Brain Injury: Predictors of Mortality in Surgical Management

Eduardo Trejo, Patricio García, Diego A. Ortega, Karla C. González, Edgar Botello, Gamaliel Hernández, Jesús A. Morales, Ángel R. Martínez
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Abstract

This is anobservational, retrospective, analytical study. The aim was todetermine a statistical basis for a future line of research based on the epidemiology of a center located in a developing country, as well as defining indirect mortality predictors. Clinical files were reviewed based on diagnosis of Traumatic Brain Injury (TBI), according to the International Classification of Diseases 10th Revision (ICD-10). Sociodemographic variables as well as treatment modality of the condition during hospitalization was recorded. The patient sample was divided into two groups. Student’s T-test was performed in variables with normal distribution and Chi-square test in independent random variables with standard normal distribution. For correlations, Pearson’s correlation coefficient was used, taking the P-value <.05 as statistically significant. A total of 150 participants were included in this study, from which 125 were male (83.3%). The average age was 28.58 ± 16.55 years. The median hospitalization time was 9 days. Forty-five patients (30%) were treated conservatively. Fifteen patients died during hospitalization. The factors considered as predictors of mortality in the general population corresponded to Motor Vehicle Accident, Frontonasal Duct Obstruction, Neuroinfection, Glasgow Coma Scale (GCS) at admission, as well as GCS at discharge. In the patients who underwent surgery, predictors of mortality corresponded to Motor Vehicle Accident, Bilateral Frontal Craniotomy, Surgical Bleeding >475 cc, Neuroinfection, as well as GCS at admission and discharge. The creation of adequate diagnostic and therapeutic algorithms in traumatic brain injury management is needed, especially in developing countries. More specific studies are needed, particularly analytical and multicentric studies, which may allow the development of these algorithms.
额窦骨折和创伤性脑损伤:手术治疗中的死亡率预测因素
这是一项观察性、回顾性和分析性研究。其目的是根据一个发展中国家中心的流行病学情况,为今后的研究方向确定统计基础,并确定间接死亡率预测因素。根据国际疾病分类第十次修订版(ICD-10)对创伤性脑损伤(TBI)的诊断,对临床档案进行了审查。此外,还记录了社会人口学变量以及住院期间的治疗方式。患者样本分为两组。对具有正态分布的变量进行学生 T 检验,对具有标准正态分布的独立随机变量进行卡方检验。在相关性方面,使用了皮尔逊相关系数,取 P 值 475 cc、神经感染以及入院和出院时的 GCS。需要为脑外伤治疗制定适当的诊断和治疗算法,尤其是在发展中国家。需要进行更具体的研究,特别是分析性研究和多中心研究,以便制定这些算法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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