PAP telehealth models and long-term therapy termination: a healthcare database analysis

Holger Woehrle, C. Schoebel, Joachim H. Ficker, A. Graml, Jürgen Schnepf, Ingo Fietze, P. Young, Michael Arzt
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Abstract

Telemonitoring-guided interventions can improve short-term positive airway pressure (PAP) therapy adherence, but long-term effects are unknown. This study investigated long-term PAP therapy termination in patients with sleep apnoea managed with standard care, telemonitoring-guided proactive care, or telemonitoring-guided proactive care+patient engagement tool. German healthcare provider data were analysed retrospectively. Individuals aged 18–100 years who started PAP from 2014–2019 and had device type/interface data were included. Time-to-termination periods were analysed using Kaplan-Meier plots and Cox proportional hazards regression, adjusted for age, sex, insurance type, and device and mask type. The per-protocol population (valid telemonitoring data) included 104 612 individuals (71% male; 95% aged >40 years). Mean follow-up was 3.3±2.0 years. The overall therapy termination rate was significantly lower in the telemonitoring-guided proactive care groupversusstandard care (20%versus27%; p<0.001), and even lower in the telemonitoring-guided care+patient engagement tool group (11%; p<0.001versusother treatment groups). Adjusted risk of therapy termination was lowerversusstandard care (hazard ratio [95% confidence interval]: 0.76 [0.74–0.78] and 0.41 [0.38–0.44] for telemonitoring-guided proactive care alone and+patient engagement). Age <50 or >59 years and use of a nasal pillows or full-face mask were significant predictors of therapy termination; male sex, use of telemonitoring-guided proactive care (± patient engagement), and private insurance were significantly associated with lower therapy termination rates. Use of telemonitoring-guided proactive care and a patient engagement tool was associated with lower rates of PAP therapy termination.
PAP 远程医疗模式与长期治疗终止:医疗保健数据库分析
远程监控指导下的干预措施可以提高短期气道正压疗法的依从性,但长期效果尚不清楚。本研究调查了通过标准护理、远程监控指导下的主动护理或远程监控指导下的主动护理+患者参与工具进行管理的睡眠呼吸暂停患者的长期气道正压疗法终止情况。我们对德国医疗机构的数据进行了回顾性分析。纳入了从 2014-2019 年开始使用 PAP 的 18-100 岁个人,他们都拥有设备类型/接口数据。使用 Kaplan-Meier 图和 Cox 比例危险回归对终止时间进行分析,并对年龄、性别、保险类型以及设备和面罩类型进行调整。按协议人群(有效远程监控数据)包括 104 612 人(71% 为男性;95% 年龄大于 40 岁)。平均随访时间为 3.3±2.0 年。远程监测指导下的主动护理组的总体治疗终止率明显低于标准护理组(20% 对 27%;P59),使用鼻枕或全脸面罩是治疗终止的重要预测因素;男性、使用远程监测指导下的主动护理(± 患者参与)和私人保险与较低的治疗终止率明显相关。使用远程监控指导下的主动护理和患者参与工具与较低的 PAP 治疗终止率有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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