Brain-Computer Interfaces for Communication in Patients with Disorders of Consciousness: A Gap Analysis and Scientific Roadmap.

IF 3.1 3区医学 Q2 CLINICAL NEUROLOGY

Neurocritical Care Pub Date : 2024-08-01 Epub Date: 2024-01-29 DOI:10.1007/s12028-023-01924-w

Nicholas D Schiff, Michael Diringer, Karin Diserens, Brian L Edlow, Olivia Gosseries, N Jeremy Hill, Leigh R Hochberg, Fatima Y Ismail, Ivo A Meyer, Charles B Mikell, Sima Mofakham, Erika Molteni, Leonard Polizzotto, Sudhin A Shah, Robert D Stevens, Daniel Thengone

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引用次数: 0

Abstract

Background: We developed a gap analysis that examines the role of brain-computer interfaces (BCI) in patients with disorders of consciousness (DoC), focusing on their assessment, establishment of communication, and engagement with their environment.

Methods: The Curing Coma Campaign convened a Coma Science work group that included 16 clinicians and neuroscientists with expertise in DoC. The work group met online biweekly and performed a gap analysis of the primary question.

Results: We outline a roadmap for assessing BCI readiness in patients with DoC and for advancing the use of BCI devices in patients with DoC. Additionally, we discuss preliminary studies that inform development of BCI solutions for communication and assessment of readiness for use of BCIs in DoC study participants. Special emphasis is placed on the challenges posed by the complex pathophysiologies caused by heterogeneous brain injuries and their impact on neuronal signaling. The differences between one-way and two-way communication are specifically considered. Possible implanted and noninvasive BCI solutions for acute and chronic DoC in adult and pediatric populations are also addressed.

Conclusions: We identify clinical and technical gaps hindering the use of BCI in patients with DoC in each of these contexts and provide a roadmap for research aimed at improving communication for adults and children with DoC, spanning the clinical spectrum from intensive care unit to chronic care.

查看原文本刊更多论文

用于意识障碍患者交流的脑机接口：差距分析与科学路线图》。

背景：我们开展了一项差距分析，研究脑机接口（BCI）在意识障碍（DoC）患者中的作用，重点关注他们的评估、交流的建立以及与环境的接触：方法："治愈昏迷运动 "召集了一个昏迷科学工作组，其中包括 16 名具有意识障碍专业知识的临床医生和神经科学家。工作组每两周召开一次在线会议，并对主要问题进行差距分析：结果：我们概述了评估 DoC 患者的 BCI 准备情况以及推动在 DoC 患者中使用 BCI 设备的路线图。此外，我们还讨论了一些初步研究，这些研究为开发用于交流的 BCI 解决方案和评估 DoC 研究参与者使用 BCI 的准备程度提供了信息。我们特别强调了异质性脑损伤引起的复杂病理生理及其对神经元信号传导的影响所带来的挑战。特别考虑了单向和双向通信之间的差异。此外，还讨论了针对成人和儿童急性和慢性DoC的植入式和非侵入式BCI解决方案：我们找出了阻碍在上述每种情况下对DoC患者使用BCI的临床和技术差距，并为旨在改善成人和儿童DoC患者交流的研究提供了路线图，研究范围涵盖从重症监护室到慢性护理的临床领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocritical Care 医学-临床神经学

CiteScore

7.40

自引率

8.60%

发文量

221

审稿时长

4-8 weeks

期刊介绍： Neurocritical Care is a peer reviewed scientific publication whose major goal is to disseminate new knowledge on all aspects of acute neurological care. It is directed towards neurosurgeons, neuro-intensivists, neurologists, anesthesiologists, emergency physicians, and critical care nurses treating patients with urgent neurologic disorders. These are conditions that may potentially evolve rapidly and could need immediate medical or surgical intervention. Neurocritical Care provides a comprehensive overview of current developments in intensive care neurology, neurosurgery and neuroanesthesia and includes information about new therapeutic avenues and technological innovations. Neurocritical Care is the official journal of the Neurocritical Care Society.