Left Atrial Low Voltage Areas Predicts Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis.

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Heart Surgery Forum Pub Date : 2024-01-21 DOI:10.59958/hsf.7043

Wenjing Zhang, Yangyang Wang, Hao Wang, Yang Shao, Qiming Dong, Songsen Li, Yunfei Gu

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引用次数: 0

Abstract

Background: Low voltage areas (LVAs) on left atrial (LA) voltage mapping correlate with atrial fibrosis. However, there is no uniform standard for the definition of LVAs, or mapping techniques and mapping rhythms, so that the predictive value of left atrial LVAs for recurrence of atrial fibrillation (AF) is uncertain. This study aimed to explore the relationship between the presence of pre-ablation left atrial LVAs and the risk of recurrent AF after catheter ablation.

Methods: The databases of PubMed, Embase, Web of science, Cochrane library, Scopus, Wanfang Datebase, China National Knowledge Infrastructure, China Biology Medicine and China Scientific Journal Datebase were searched from inception to 31 July 2023. Relevant studies regarding left atrial LVAs prior to ablation to predict postoperative recurrence of AF were identified and analyzed. The efficacy endpoints were defined as the recurrence of atrial arrhythmia lasting over 30 s.

Results: A total of 12 studies with 1070 patients were included. We found the presence of pre-ablation left atrial LVAs correlated with the risk of recurrent AF after ablation (hazard ratio (HR) = 2.87, 95% confidence interval (CI): 2.33-3.52). The presence of pre-ablation left atrial LVAs can predict the risk of recurrent AF after ablation both in the follow-up duration ≤12 months group and follow-up duration >12 months group (follow-up duration ≤12 months: HR = 2.93, 95% CI: 2.20-3.90; follow-up duration >12 months: HR = 2.80, 95% CI: 2.09-3.77). The presence of pre-ablation left atrial LVAs correlated with the risk of recurrent AF after ablation in paroxysmal AF (HR = 2.89, 95% CI: 1.97-4.24).

Conclusions: The presence of pre-ablation left atrial LVAs correlate with the risk of recurrent AF after catheter ablation.

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左心房低电压区可预测导管消融术后心房颤动的复发：元分析

背景：左心房（LA）电压图上的低电压区（LVA）与心房纤维化相关。然而，低电压区的定义、绘图技术和绘图节奏都没有统一的标准，因此左心房低电压区对房颤（AF）复发的预测价值并不确定。本研究旨在探讨消融术前左心房LVA的存在与导管消融术后房颤复发风险之间的关系：方法：检索从开始到 2023 年 7 月 31 日的 PubMed、Embase、Web of science、Cochrane library、Scopus、万方数据库、中国国家知识基础设施、中国生物医学和中国科技期刊数据库。确定并分析了有关消融术前左心房LVA预测房颤术后复发的相关研究。疗效终点定义为持续 30 秒以上的房性心律失常复发：结果：共纳入了 12 项研究，1070 名患者。我们发现，消融前左心房LVA的存在与消融后房颤复发的风险相关（危险比（HR）= 2.87，95% 置信区间（CI）：2.33-3.52）。在随访时间≤12 个月组和随访时间＞12 个月组中，消融前左心房 LVA 的存在可预测消融后房颤复发的风险（随访时间≤12 个月：HR = 2.93，95% 置信区间（CI）：2.33-3.52）：HR=2.93，95% CI：2.20-3.90；随访时间>12 个月：HR = 2.80，95% CI：2.09-3.77）。在阵发性房颤中，消融前左心房LVA的存在与消融后房颤复发的风险相关（HR = 2.89，95% CI：1.97-4.24）：结论：消融前左心房LVA的存在与导管消融后房颤复发的风险相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Heart Surgery Forum 医学-外科

CiteScore

1.20

自引率

16.70%

发文量

130

审稿时长

6-12 weeks

期刊介绍： The Heart Surgery Forum® is an international peer-reviewed, open access journal seeking original investigative and clinical work on any subject germane to the science or practice of modern cardiac care. The HSF publishes original scientific reports, collective reviews, case reports, editorials, and letters to the editor. New manuscripts are reviewed by reviewers for originality, content, relevancy and adherence to scientific principles in a double-blind process. The HSF features a streamlined submission and peer review process with an anticipated completion time of 30 to 60 days from the date of receipt of the original manuscript. Authors are encouraged to submit full color images and video that will be included in the web version of the journal at no charge.