{"title":"[Elderly onset Crohn's disease: Clinical and therapeutic features].","authors":"Hanen Elloumi, Habiba Dabbebi","doi":"10.1684/pnv.2023.1129","DOIUrl":null,"url":null,"abstract":"<p><p>Crohn's disease (CD) is a pathology that typically affects young people. With the aging of the population, there is an increase of its incidence in the elderly. Several studies have compared the clinical and therapeutic features of the CD in the elderly and young patients with discordant results. The objective of this work was to identify the clinical and therapeutic characteristics of elderly onset CD. The clinical presentation of CD in the elderly has some peculiarities. It seems that the disease has a less severe profile. The ileal and colic locations as well as the inflammatory phenotype are the most frequent. The treatment of elderly patients poses a real challenge to the clinician because of the field particularity and the lack of large-scale data in the literature. The frequency of comorbidities and polymedications is at the origin of the lower prescription of immunomodulators and biotherapies and the frequency of postoperative complications and immunosuppressive treatments.</p>","PeriodicalId":51244,"journal":{"name":"Geriatrie et Psychologie Neuropsychiatrie De Vieillissement","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Geriatrie et Psychologie Neuropsychiatrie De Vieillissement","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1684/pnv.2023.1129","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Crohn's disease (CD) is a pathology that typically affects young people. With the aging of the population, there is an increase of its incidence in the elderly. Several studies have compared the clinical and therapeutic features of the CD in the elderly and young patients with discordant results. The objective of this work was to identify the clinical and therapeutic characteristics of elderly onset CD. The clinical presentation of CD in the elderly has some peculiarities. It seems that the disease has a less severe profile. The ileal and colic locations as well as the inflammatory phenotype are the most frequent. The treatment of elderly patients poses a real challenge to the clinician because of the field particularity and the lack of large-scale data in the literature. The frequency of comorbidities and polymedications is at the origin of the lower prescription of immunomodulators and biotherapies and the frequency of postoperative complications and immunosuppressive treatments.
克罗恩病（CD）是一种通常影响年轻人的病症。随着人口老龄化，老年人的发病率也在增加。有几项研究比较了老年和年轻患者克罗恩病的临床和治疗特点，但结果并不一致。本研究旨在确定老年 CD 的临床和治疗特征。老年 CD 的临床表现有一些特殊性。该病似乎病情较轻。回肠和绞痛部位以及炎症表型最为常见。由于领域的特殊性和缺乏大规模的文献数据，老年患者的治疗对临床医生来说是一个真正的挑战。合并症和多药并存是导致免疫调节剂和生物疗法处方量减少、术后并发症和免疫抑制治疗频发的原因。
期刊介绍：
D''une qualité scientifique reconnue cette revue est, la première revue francophone gériatrique et psychologique indexée dans les principales bases de données internationales. Elle couvre tous les aspects médicaux, psychologiques, sanitaires et sociaux liés au suivi et à la prise en charge de la personne âgée.
Que vous soyez psychologues, neurologues, psychiatres, gériatres, gérontologues,... vous trouverez à travers cette approche originale et unique, un veritable outil de formation, de réflexion et d''échanges indispensable à votre pratique professionnelle.
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