Study of the state of intermediate metabolism and antiradical defense of the body of meat quail during the elimination of mycotoxin

Abstract

In the last decade, a new promising direction to reduce the risk of T-2 toxicosis at domestic poultry enterprises has been the rational use of antioxidants in the formulation of compound feeds. The purpose of the research is to determine the effect of the antioxidants santoquin (santoquin) and vitamin E in the composition of feed based on wheat grain, sorghum and rapeseed meal with a tolerant level of T-2 toxin on the state of intermediate metabolism and anti-radical protection of the body of meat quails. We have substantiated new data on the advisability of jointly introducing the antioxidants santoquin at a dose of 150 g/t and vitamin E at a dose of 25 thousand IU/t of feed into the composition of feed based on wheat grain, sorghum and rapeseed meal with a tolerant level of T-2 toxin to optimize the meat quail hematopoietic function of the body. The tested antioxidants, when fed in combination, contributed to the improvement of protein, carbohydrate, lipid and mineral metabolism in quails of the 3rd experimental group. Due to the synergistic effect of antioxidants in the composition of diets, an increase in protective functions in the body of quails of the 3rd experimental group was noted due to an increase in lysozyme activity in blood samples by 3,00% (P>0,95) and bactericidal activity - by 8,30% (P>0,95) than in the control group. While ensuring better detoxification of T-2 toxin in comparison with control analogues, meat quails of the 3rd experimental group improved the antioxidant defense of the body due to an increase in the enzymatic activity of glutathione reductase in the blood by 25,34% (P>0,95), alkaline phosphatase - by 18,34% (P>0,95) with a parallel decrease in catalase activity - by 9,54% (P>0,95), the level of conjugated dienes - by 2,28 times (P>0,95) and malondialdehyde - by 1,33 times (P>0,95).