Detection of Bowel and Mesenteric Injuries Using Deep Learning Computer Vision Models

Neal Mahajan, S. Steenburg, Peter Gunderman, John Burns, Arya Iranmanesh
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Abstract

Background/Objective:While only seen in 1-5% of patients who undergo a CT (computed tomography) scan, blunt bowel and mesenteric injuries (BMI) are associated with significantly increased morbidity and mortality. A significant cause of the increased morbidity of BMI is due to the difficulty of diagnosis from clinical and imaging information which leads to delay in diagnosis. Accurate and timely diagnosis is vital to reduce the morbidity of BMI. Methods:For this project, our primary objective is to create a binary prediction model that determines if a patient has BMI based on their abdominal CT scans. Due to the importance of the early and definitive diagnosis of BMI in trauma patients, an extension of this project will seek to introduce explainability into the model to highlight which features on the CT scan caused the model to make its prediction. The patients with BMI were sourced from a trauma registry that recorded trauma cases from IU Health with relevant diagnosis codes. The images from our search will be reduced to the relevant slices for diagnosis of BMI and then used to train an ML model to makea yes/no prediction from the image. Once the model is trained, testing data will be evaluated on the model and the gradient vectors from the model during inference will be used to create a heatmap with GRAD-CAM that illustrates what portions of the image were relevant for the decision made by the algorithm. Future Directions:Using the collected abdominal CTs, we can train our machine learning pipeline to detect BMI. Based on the performance of the model, we will determine if we need to collect more data. Then, we can evaluate the explainability of the model using GRAD-CAM and compareperformance of the ML model to the performance of expert and trainee radiologists.
利用深度学习计算机视觉模型检测肠道和肠系膜损伤
背景/目的:在接受 CT(计算机断层扫描)扫描的患者中,钝性肠道和肠系膜损伤(BMI)仅占 1-5%,但其发病率和死亡率却显著增加。钝性肠道和肠系膜损伤发病率增加的一个重要原因是临床和影像学信息难以诊断,导致诊断延误。准确及时的诊断对于降低 BMI 发病率至关重要。方法:在本项目中,我们的主要目标是创建一个二元预测模型,根据患者的腹部 CT 扫描结果来确定其是否患有 BMI。由于早期明确诊断创伤患者 BMI 的重要性,本项目的一个延伸部分将寻求在模型中引入可解释性,以突出 CT 扫描上的哪些特征导致模型做出预测。有 BMI 的患者来自创伤登记处,该登记处记录了来自 IU Health 并带有相关诊断代码的创伤病例。我们将把搜索到的图像缩减为用于诊断 BMI 的相关切片,然后用于训练 ML 模型,以便根据图像做出是/否预测。模型训练完成后,将对模型的测试数据进行评估,推理过程中模型的梯度向量将用于使用 GRAD-CAM 创建热图,说明图像的哪些部分与算法做出的决定相关。未来方向:利用收集到的腹部 CT,我们可以训练机器学习管道来检测 BMI。根据模型的性能,我们将确定是否需要收集更多数据。然后,我们可以使用 GRAD-CAM 评估模型的可解释性,并将 ML 模型的性能与放射科专家和实习医生的性能进行比较。
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