Management of Giant Cell Tumor by Curettage and Bone graft in Weight Bearing Bone - A Study Done in CENTRAL MEDICAL COLLEGE.

Md Kawser Hamid, Md Mainul Hasan, Md Arifur Rahaman, Mohammad Emdadul Hoque, Md Safiqur Rahman Patwary, Minhazur Rahman
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Abstract

Background: Giant cell tumor of bone (GCT) has been characterized as benign but often locally aggressive neoplasm that commonly occurs in proximity to weight bearing bone. Management of giant cell tumor of bone by curettage and bone graft in weight bearing bone is an effective method. This prospective experimental study was conducted among the patients with histologically proved giant-cell tumor who were admitted in the Department of orthopedic surgery, Central Medical College Hospital over a period of 18 months from January 2018 to June 2020. A total of 12 consecutive patients with histologically proved giant-cell tumour were included in the study. Majority (55.6%) of patient was in 3rd decade and male female ratio was 1:1.3. More than one fourth (25%) of the patients had GCT in the lower end of right femur, 33.3% in lower end of left femur, 25% in upper end of tibia, 16.7% in lower end of tibia and all patients had painful gait and swelling. According to campanacci grading, Grade-2 was found in all patients, and giant cell tumor was found in all patients, as evaluated by pre-operative biopsy. Cosmetically near normal appearance was found in 88.9% and 88.9% were able to do normal daily work. According to Schatzker and Lamber (1979) criteria excellent outcome was found in 41.7%, good in 50%, fair in 8.3%. Surgery in the form of intralesional curettage and filling the cavity with bone graft resulted in excellent relief of pain, cosmetically near normal appearance and patients were able to do normal daily work. Central Medical College Journal Vol 7 No 1 January 2023 Page: 7-12
在负重骨中通过刮宫和植骨治疗巨细胞瘤--中央医科大学的一项研究。
背景:骨巨细胞瘤(GCT)是一种良性肿瘤,但通常具有局部侵袭性,常发生在负重骨附近。对骨质巨细胞瘤进行刮除和负重骨移植是一种有效的治疗方法。这项前瞻性实验研究的对象是中央医学院附属医院骨外科在2018年1月至2020年6月的18个月期间收治的经组织学证实的巨细胞瘤患者。研究共纳入了 12 名经组织学证实的巨细胞瘤连续患者。大部分(55.6%)患者年龄在三十年左右,男女比例为 1:1.3。超过四分之一(25%)的患者股骨巨细胞瘤发生在右股骨下端,33.3%发生在左股骨下端,25%发生在胫骨上端,16.7%发生在胫骨下端,所有患者均伴有步态疼痛和肿胀。根据 Campanacci 分级,所有患者均为 2 级,术前活检结果显示,所有患者均发现巨细胞瘤。88.9%的患者外观接近正常,88.9%的患者能够从事正常的日常工作。根据 Schatzker 和 Lamber(1979 年)的标准,41.7% 的患者疗效极佳,50% 的患者疗效良好,8.3% 的患者疗效一般。手术的形式是进行区域内刮除并用植骨填充空腔,结果是疼痛得到了很好的缓解,外观接近正常,患者能够从事正常的日常工作。中央医学院学报》第 7 卷第 1 期,2023 年 1 月,第 7-12 页:7-12
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