Carotid Revascularization Is Associated With Improved Mood in Patients With Advanced Carotid Disease.

IF 7.5 1区 医学 Q1 SURGERY
Annals of surgery Pub Date : 2025-04-01 Epub Date: 2024-01-23 DOI:10.1097/SLA.0000000000006216
Bahaa Succar, Ying-Hui Chou, Chiu-Hsieh Hsu, Steven Rapcsak, Theodore Trouard, Wei Zhou
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引用次数: 0

Abstract

Objective: To investigate the impact of carotid interventions on the mental well-being of patients with carotid stenosis.

Background: Ongoing research highlights the effect of carotid interventions on neurocognitive function in patients with advanced carotid atherosclerosis. However, data regarding the impact of carotid revascularization on mood are scarce.

Methods: A total of 157 patients undergoing carotid revascularization were prospectively recruited. The primary outcome was depressive mood, evaluated preoperatively and at 1-, 6-, and 12-month postintervention using the long form of the geriatric depression scale (GDS-30) questionnaire. Other tests were also used to assess cognition at the respective timepoints. Statistical analyses were performed to assess the postoperative outcomes compared with baseline.

Results: Baseline depression (GDS>9) was observed in 49 (31%) subjects, whereas 108 (69%) patients were not depressed (GDS≤9). The average preoperative GDS score was 15.42 ± 4.40 (14.2-16.7) and 4.28 ±2.9 (3.7-4.8) in the depressed and nondepressed groups, respectively. We observed a significant improvement in GDS scores within the depressed group at 1 month ( P =0.002), 6 months ( P =0.027), and 1 year ( P <0.001) postintervention compared with pre-op, whereas the nondepressed group had similar post-op GDS scores at all timepoints compared with baseline. Significant improvement in measures of executive function was seen in nondepressed patients at all 3 timepoints, whereas depressed patients showed an improvement at 1-year follow-up.

Conclusions: Our study highlights improvement in mood among patients with advanced carotid disease who screened positive for depression at baseline. Further studies with larger sample sizes are warranted to investigate the association between depression, carotid disease, and carotid intervention.

颈动脉血运重建与晚期颈动脉疾病患者情绪改善有关。
目的:探讨颈动脉介入治疗对颈动脉狭窄患者精神状况的影响:研究颈动脉介入治疗对颈动脉狭窄患者精神状况的影响:正在进行的研究强调了颈动脉介入治疗对晚期颈动脉粥样硬化患者神经认知功能的影响。然而,有关颈动脉血运重建对情绪影响的数据却很少:方法:前瞻性地招募了157名接受颈动脉血运重建术的患者。主要结果是抑郁,使用老年抑郁量表(GDS-30)长表进行术前、干预后 1、6 和 12 个月的评估。其他测试也用于评估各时间点的认知能力。与基线相比,对术后结果进行了统计分析:结果:49(31%)名受试者出现基线抑郁(GDS>9),而 108(69%)名患者没有抑郁(GDS≤9)。抑郁组和非抑郁组的术前 GDS 平均得分分别为 15.42 ± 4.40(14.2-16.7)和 4.28 ±2.9(3.7-4.8)。我们观察到,抑郁组患者的 GDS 评分在 1 个月(P=0.002)、6 个月(P=0.027)和 1 年(PC结论:我们的研究强调了基线抑郁筛查呈阳性的晚期颈动脉疾病患者的情绪改善情况。有必要进行样本量更大的进一步研究,以探讨抑郁、颈动脉疾病和颈动脉干预之间的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annals of surgery
Annals of surgery 医学-外科
CiteScore
14.40
自引率
4.40%
发文量
687
审稿时长
4 months
期刊介绍: The Annals of Surgery is a renowned surgery journal, recognized globally for its extensive scholarly references. It serves as a valuable resource for the international medical community by disseminating knowledge regarding important developments in surgical science and practice. Surgeons regularly turn to the Annals of Surgery to stay updated on innovative practices and techniques. The journal also offers special editorial features such as "Advances in Surgical Technique," offering timely coverage of ongoing clinical issues. Additionally, the journal publishes monthly review articles that address the latest concerns in surgical practice.
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