A Review of the Literature, the Detection and Treatment of Colorectal Cancer during Pregnancy: A Case Study!

Mirza Faraz Saeed, Taima Almubarak, Sara Khalaf, Ahmet Aslan, Isam Mazin Juma
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Abstract

Background: Colorectal cancer (CRC) during pregnancy is rare and presents diagnostic and therapeutic challenges.

Aim: This case report focuses on a patient who presented with colorectal cancer during pregnancy.

Case description: A 45-year-old female primigravid, pregnant woman, in the 20th week of gestation presented with complaints of multiple episodes of bloody diarrhea and tenesmus for the past 3 weeks. This was accompanied by poor appetite and weight loss (15 kg) since the onset of pregnancy. The patient also complained of lower back and abdominal pain. Investigations confirmed an obstructing rectosigmoid mass (15 cm) that could not be passed. The patient's pregnancy was terminated, and chemotherapeutic treatment was initiated.

Clinical significance: With the clinical manifestations of CRC during pregnancy being non-specific, tumors are usually discovered at an advanced stage. This poses a challenge for physicians to treat such cases. This case contributes to the growing literature on pregnancies complicated by CRC and highlights the importance of high clinical suspicion and the need for a multidisciplinary team in tailoring treatment regimens in accordance with patient-centered care.

Conclusion: This case report highlights the rarity of colorectal cancer during pregnancy and the challenges faced in the diagnoses and treatment.

How to cite this article: Saeed MF, Almubarak T, Khalaf S, et al. A Review of the Literature, the Detection and Treatment of Colorectal Cancer during Pregnancy: A Case Study! Euroasian J Hepato-Gastroenterol 2023;13(2):159-162.

Abstract Image

Abstract Image

文献综述:孕期大肠癌的检测和治疗:病例研究!
背景:妊娠期结直肠癌(CRC)非常罕见,给诊断和治疗带来了挑战。目的:本病例报告的重点是一名妊娠期结直肠癌患者:一名 45 岁的初产孕妇在妊娠第 20 周时主诉在过去 3 周内多次出现血性腹泻和便秘。自怀孕以来,她一直食欲不振,体重下降(15 千克)。患者还主诉下背部和腹部疼痛。检查证实,直肠乙状结肠有一个无法排出的梗阻性肿块(15 厘米)。患者的妊娠被终止,并开始接受化疗:临床意义:由于妊娠期 CRC 的临床表现无特异性,肿瘤通常在晚期才被发现。这给医生治疗此类病例带来了挑战。本病例为越来越多的关于妊娠期并发 CRC 的文献做出了贡献,并强调了临床高度怀疑的重要性以及多学科团队根据以患者为中心的护理原则制定治疗方案的必要性:本病例报告强调了妊娠期结直肠癌的罕见性以及在诊断和治疗中面临的挑战:Saeed MF, Almubarak T, Khalaf S, et al. A Review of the Literature, the Detection and Treatment of Colorectal Cancer during Pregnancy:病例研究!Euroasian J Hepato-Gastroenterol 2023;13(2):159-162.
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