Comparison of HMGB1, RAGE, TLR4, and NF-κB levels in children and adolescents diagnosed with autism spectrum disorder with healthy controls

IF 1.5 4区医学 Q2 EDUCATION, SPECIAL

International Journal of Developmental Disabilities Pub Date : 2024-01-13 DOI:10.1080/20473869.2023.2301185

Esra Kıyat, Evrim Aktepe, Duygu Kumbul Doğuç, Mehmet Bedir, Emre Ertürk, Ümit Işık

引用次数: 0

Abstract

The objective of our study is to clarify the involvement of the HMGB1/RAGE/TLR4/NF-kB axis, a crucial component in inflammation, in the etiopathogenesis of autism spectrum disorder (ASD).We analyze...

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被诊断患有自闭症谱系障碍的儿童和青少年与健康对照组的 HMGB1、RAGE、TLR4 和 NF-κB 水平比较

我们的研究旨在阐明作为炎症关键组成部分的HMGB1/RAGE/TLR4/NF-kB轴参与自闭症谱系障碍（ASD）的发病机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Developmental Disabilities Multiple-

CiteScore

4.10

自引率

9.50%

发文量

期刊介绍： The IJDD publishes scientific articles on work dealing with different approaches to the habilitation problems of people with an intellectual disability. The Journal covers the entire spectrum of intellectual disabilities, and is concerned with definitions, IQ, genetic predisposition, evaluation of abilities, learning interventions, challenging behaviour, medication, attitudes to death and bereavement, sexuality, legal aspects, WHO, NICE and other governmental guidelines, care in the community, advocacy, stress and coping strategies for families and carers - though this is not an exhaustive list. The unifying theme is that all of these aspects should be of practical help for those with intellectual disabilities or those caring for persons with intellectual disabilities. Emphasis is placed on the practical implications of the work of educationists, instructors, nurses, occupational and other therapists, psychiatrists, psychologists and social workers, whether taking place in a hospital setting or in community care. The Journal accepts contributions from anywhere in the world but they must be written in acceptable and fluent English, avoiding technical jargon as far as possible in view of the wide readership. The IJDD puts much emphasis on the practical application of scientific findings, and prospective contributors should keep in mind that acceptance of a manuscript for publication will depend to a great extent on its direct relevance to habilitation work. Readers of the IJDD expect that articles should give them some scientific help and insight in their practical work.