Biocatalysts for biomethanol production: Advancements and future prospects

R. K. Srivastava, P. Sarangi, U. K. Sahoo, Tarun Kumar Thakur, Harikesh B. Singh, Sanjukta Subudhi
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Abstract

Biomethanol, a renewable and sustainable alternative to traditional fossil-fuel-derived methanol, has garnered considerable attention as a potential solution to mitigate greenhouse gas emissions and dependence on non-renewable resources. The utilization of biocatalysts in biomethanol production offers a promising avenue to achieve environmentally friendly and economically viable processes. Paper highlights the biocatalytic pathways involved in biomethanol synthesis. Particular emphasis is placed on microbial biocatalysts, such as methanogenic archaea and certain bacteria, which possess the unique capability of converting carbon dioxide and hydrogen into methanol through a series of enzymatic reactions. Additionally, enzyme-based systems derived from various microorganisms and genetically engineered organisms are also discussed as potential biocatalysts for biomethanol synthesis. Paper also delves into the current challenges and limitations faced in harnessing biocatalysts for biomethanol production. These challenges include substrate availability, low conversion rates, enzyme stability, and process scalability. Several strategies to address these issues are highlighted, including metabolic engineering, synthetic biology, and bioprocess optimization techniques. The advantages of utilizing biocatalysts for biomethanol production are outlined. Biocatalytic routes offer the advantage of operating under mild conditions, which reduces energy consumption and minimizes the production of unwanted by-products. Furthermore, the utilization of renewable feedstocks, such as carbon dioxide captured from industrial emissions or waste streams, enhances the sustainability of the process. The final section discusses future prospects and potential research directions in the field of biocatalytic biomethanol production. Advances in biotechnology, omics technologies, and computational modeling are poised to accelerate the discovery and optimization of novel biocatalysts, thereby unlocking the full potential of biomethanol as a sustainable fuel and chemical precursor. The use of biocatalysts for biomethanol production offers an attractive approach to establish a green and circular economy. With ongoing research and technological advancements, the field holds significant promise for reducing carbon emissions and transitioning towards a more sustainable energy landscape. However, to fully realize the potential of biocatalytic biomethanol production, interdisciplinary collaboration and concerted efforts are required to address existing challenges.
生产生物甲醇的生物催化剂:进展与前景
生物甲醇是传统化石燃料甲醇的可再生和可持续替代品,作为减少温室气体排放和对不可再生资源依赖的潜在解决方案,生物甲醇已经引起了广泛关注。在生物甲醇生产中利用生物催化剂为实现环境友好型和经济可行型工艺提供了一条大有可为的途径。论文重点介绍了生物甲醇合成所涉及的生物催化途径。论文特别强调了微生物生物催化剂,如产甲烷古细菌和某些细菌,它们具有通过一系列酶促反应将二氧化碳和氢转化为甲醇的独特能力。此外,论文还讨论了从各种微生物和基因工程生物中提取的基于酶的系统,将其作为生物甲醇合成的潜在生物催化剂。论文还深入探讨了目前利用生物催化剂生产生物甲醇所面临的挑战和限制。这些挑战包括底物的可用性、低转化率、酶的稳定性和工艺的可扩展性。重点介绍了解决这些问题的几种策略,包括代谢工程、合成生物学和生物工艺优化技术。概述了利用生物催化剂生产生物甲醇的优势。生物催化路线具有在温和条件下操作的优势,可降低能耗并最大限度地减少不需要的副产品的产生。此外,利用可再生原料(如从工业排放或废物流中捕获的二氧化碳)可增强工艺的可持续性。最后一节讨论了生物催化生物甲醇生产领域的未来前景和潜在研究方向。生物技术、omics 技术和计算建模的进步将加速新型生物催化剂的发现和优化,从而释放生物甲醇作为可持续燃料和化学前体的全部潜力。使用生物催化剂生产生物甲醇为建立绿色和循环经济提供了一种极具吸引力的方法。随着研究的不断深入和技术的不断进步,该领域在减少碳排放和向更可持续的能源格局过渡方面大有可为。然而,要充分发挥生物催化生物甲醇生产的潜力,需要跨学科合作和共同努力来应对现有挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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