Patient selection criteria for transcatheter implantation of aortic valve

M.B. Todurov, O. Zelenchuk, A. V. Khokhlov, M. Stan, N.O. Yashchenko
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Abstract

The aim – to conduct a literature review, analyze and, based on our own results, present an algorithm for choosing the tactics of surgical treatment of patients with severe aortic stenosis.Materials and methods. In this prospective study, the medical records of adult patients (from 18 years of age) who underwent surgical or transcatheter aortic valve replacement at the Heart Institute of the Ministry of Health of Ukraine, between 2018 and 2023 were analyzed.Results. The algorithm for the selection of surgical treatment of patients included in the study was built based on a thorough analysis of the anamnesis, clinical, laboratory and instrumental examination data. An important stage in choosing the optimal surgical tactics is the assessment of the development of intraoperative and postoperative complications according to the EuroSCORE and STS SCORE scales, which are most widely used in cardiac surgery practice and allow predicting the complicated course of the early postoperative period in patients with acquired valvular heart defects. Although there is an increasing trend towards TAVI in younger, lower-risk patients, the more frequent possibility of residual paravalvular insufficiency and the need for permanent pacemaker implantation should be considered. As the experience of interventional cardiologists increases and new valve designs and delivery systems are developed, better clinical outcomes and lower complication rates can be expected, which will contribute to the expansion of indications for TAVI.Conclusions. Today, TAVI remains the only way to correct aortic valve defects for inoperable patients with severe symptomatic aortic stenosis. Based on the results of several randomized controlled trials, TAVI is associated with a much lower rate of postoperative complications and a faster recovery, and should be the method of choice in all high surgical risk patients and a competitive alternative to aortic valve replacement in intermediate risk patients.
经导管植入主动脉瓣的患者选择标准
目的--进行文献综述、分析,并根据我们自己的结果,提出一种算法,用于选择严重主动脉瓣狭窄患者的手术治疗策略。在这项前瞻性研究中,对 2018 年至 2023 年期间在乌克兰卫生部心脏研究所接受手术或经导管主动脉瓣置换术的成年患者(18 岁以上)的病历进行了分析。在对患者的病史、临床、实验室和仪器检查数据进行全面分析的基础上,建立了为研究对象选择手术治疗的算法。选择最佳手术策略的一个重要阶段是根据 EuroSCORE 和 STS SCORE 量表评估术中和术后并发症的发展情况,这两个量表在心脏外科实践中应用最为广泛,可以预测后天性瓣膜缺损患者术后早期的复杂病程。虽然在年轻、风险较低的患者中进行 TAVI 的趋势越来越明显,但应考虑到更常见的瓣膜旁功能不全残留的可能性以及永久起搏器植入的必要性。随着介入心脏病专家经验的增加以及新瓣膜设计和输送系统的开发,预计会有更好的临床效果和更低的并发症发生率,这将有助于扩大 TAVI 的适应症。如今,对于无法手术的严重症状性主动脉瓣狭窄患者来说,TAVI 仍是矫正主动脉瓣缺损的唯一方法。根据多项随机对照试验的结果,TAVI 的术后并发症发生率更低,术后恢复更快,应成为所有高手术风险患者的首选方法,也是中度风险患者主动脉瓣置换术的竞争性替代方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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