Left ventricular hypertrophy (LVH) in different stages of chronic kidney disease (CKD) patients and its correlation with anaemia

Journal of Bangladesh College of Physicians and Surgeons Pub Date : 2024-01-10 DOI:10.3329/jbcps.v42i1.70638

Omma Tahara, Pradip K Dutta

{"title":"Left ventricular hypertrophy (LVH) in different stages of chronic kidney disease (CKD) patients and its correlation with anaemia","authors":"Omma Tahara, Pradip K Dutta","doi":"10.3329/jbcps.v42i1.70638","DOIUrl":null,"url":null,"abstract":"Background : Chronic kidney disease (CKD) is a public health problem that increases the risk of cardiovascular morbidity and mortality. Heart failure with preserved ejection fraction characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction is a common cardiovascular complication of CKD. Anaemia is present in both dialysis & non dialysis CKD patients. Anaemia causes left ventricular hypertrophy (LVH) which in turn leads to increases morbidity and mortality in CKD, even before progression of chronic kidney disease (CKD) to end stage renal disease (ESRD). Our study is aimed at to evaluate the prevalence of left ventricular hypertrophy (LVH) and its correlation with anaemia in hospitalized CKD patients.\nMaterials and Methods : A cross-sectional study was done on 50 patients of different stages of CKD admitted in the chittagong medical college hospital (CMCH). All the clinical data were reviewed and recorded. Data was analyzed by SPSS-18 and p value <0.05 was considered statistically significant.\nResults : Majority of study population 64% was male, 36% was female. Most of the male patient (40%) of the study population were having abnormal left ventricular mass index (>130 gm/m2). More patients with severe left ventricular hypertrophy were found in stage 5 of CKD in female and male which was 8 and 23 respectively. Regarding correlation of Hb% with LVMI there was a significant negative correlation was found (r= -0.420, p = 0.003) between them means if Hb% decreases LVMI level increases. It was also found in male and female patients separately ( for male r = -0.778, p = 0.001 and for female r = -0.746, p = 0.001).\nConclusion : Anemia is widely prevalent in our CKD patients. Severity of anemia is correlated to left ventricular hypertrophy in these patients. Hence correction of anemia early in these group of patients can halt or prevent cardiovascular morbidity and mortality.\nJ Bangladesh Coll Phys Surg 2024; 42: 25-30","PeriodicalId":105305,"journal":{"name":"Journal of Bangladesh College of Physicians and Surgeons","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Bangladesh College of Physicians and Surgeons","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/jbcps.v42i1.70638","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background : Chronic kidney disease (CKD) is a public health problem that increases the risk of cardiovascular morbidity and mortality. Heart failure with preserved ejection fraction characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction is a common cardiovascular complication of CKD. Anaemia is present in both dialysis & non dialysis CKD patients. Anaemia causes left ventricular hypertrophy (LVH) which in turn leads to increases morbidity and mortality in CKD, even before progression of chronic kidney disease (CKD) to end stage renal disease (ESRD). Our study is aimed at to evaluate the prevalence of left ventricular hypertrophy (LVH) and its correlation with anaemia in hospitalized CKD patients. Materials and Methods : A cross-sectional study was done on 50 patients of different stages of CKD admitted in the chittagong medical college hospital (CMCH). All the clinical data were reviewed and recorded. Data was analyzed by SPSS-18 and p value <0.05 was considered statistically significant. Results : Majority of study population 64% was male, 36% was female. Most of the male patient (40%) of the study population were having abnormal left ventricular mass index (>130 gm/m2). More patients with severe left ventricular hypertrophy were found in stage 5 of CKD in female and male which was 8 and 23 respectively. Regarding correlation of Hb% with LVMI there was a significant negative correlation was found (r= -0.420, p = 0.003) between them means if Hb% decreases LVMI level increases. It was also found in male and female patients separately ( for male r = -0.778, p = 0.001 and for female r = -0.746, p = 0.001). Conclusion : Anemia is widely prevalent in our CKD patients. Severity of anemia is correlated to left ventricular hypertrophy in these patients. Hence correction of anemia early in these group of patients can halt or prevent cardiovascular morbidity and mortality. J Bangladesh Coll Phys Surg 2024; 42: 25-30

查看原文本刊更多论文

不同阶段慢性肾脏病（CKD）患者的左心室肥大（LVH）及其与贫血的关系

背景：慢性肾脏病（CKD）是一个增加心血管发病率和死亡率风险的公共卫生问题。以左心室肥厚（LVH）和舒张功能障碍为特征的射血分数保留型心力衰竭是慢性肾脏病常见的心血管并发症。透析和非透析的慢性肾脏病患者都会出现贫血。贫血会导致左心室肥厚（LVH），进而增加慢性肾脏病的发病率和死亡率，甚至在慢性肾脏病发展到终末期肾脏病（ESRD）之前就会出现这种情况。我们的研究旨在评估住院的慢性肾脏病患者中左心室肥大（LVH）的患病率及其与贫血的相关性。材料和方法：我们对吉大港医学院附属医院（CMCH）收治的 50 名不同阶段的慢性肾脏病患者进行了横断面研究。对所有临床数据进行了审查和记录。数据采用 SPSS-18 进行分析，P 值为 130 gm/m2）。严重左心室肥厚的患者多见于 CKD 第 5 阶段，女性为 8 例，男性为 23 例。关于 Hb% 与 LVMI 的相关性，发现两者之间存在显著的负相关（r= -0.420，p = 0.003），这意味着如果 Hb% 降低，LVMI 水平就会升高。在男性和女性患者中也分别发现了这一点（男性 r = -0.778，p = 0.001；女性 r = -0.746，p = 0.001）。贫血的严重程度与这些患者的左心室肥大有关。因此，尽早纠正这类患者的贫血可以阻止或预防心血管疾病的发病率和死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Bangladesh College of Physicians and Surgeons

自引率

0.00%

发文量