Anorectal malformation: Audit of management in a major tertiary institution in Ghana

Fareeda Galley , Arkoh Ebenezer Ameyaw , Abiboye Yifieyeh , Afua Hesse
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Abstract

Background

Anorectal malformation (ARM) remains a significant challenge to the child and paediatric surgeons. Its rarity is relative in Sub-Saharan Africa, where there are few specialized centres for management. This study aimed to describe the presentations, management, and preliminary outcomes of ARM in a major specialized centre.

Methods

A prospective observational study, with a two-year follow-up was conducted for children (up to 15 years) who presented with ARM at the Paediatric Surgery Unit between November 2020 and July 2021.

Results

Sixty-one (61) patients (M: F = 1:0.96) were studied. 28.27 % of the ARM's were detected on day one of birth. More than two thirds of the cohort (70.5 %) was first detected by mothers. The remainder (29.5 %) were detected by health professionals. Majority, 88.2 %, presented late (>24hours). 34(55.4 %) presented in a stable state, 20(32.79 %) with acute intestinal obstruction and 4(6.56 %) with sepsis. Associated congenital anomalies were observed in 7(11.48 %) of patients. All the children had a staged procedure (colostomy, PSARP and closure of colostomy). The mean duration between colostomy creation and PSARP was 7.02 +/- 2.05 months, while the mean duration between PSARP and colostomy reversal was eight months. The complication and mortality rates after all the staged procedures were 39.3 % and 2.2 %, respectively. 5.2 % had persistent faecal soiling while 3.5 % had persistent constipation at 2 years. There were no anal strictures or rectal prolapse.

Conclusion

Surgical outcomes of children with ARM are generally good, although there were late and unstable presentations to the hospital. Late identification of ARM by health professionals lead to late presentation.

肛门直肠畸形:加纳一所大型高等院校的管理审计
背景肛门直肠畸形(ARM)仍然是儿童和儿科外科医生面临的重大挑战。在撒哈拉以南的非洲地区,这种疾病相对罕见,因为那里几乎没有专门的治疗中心。本研究旨在描述一家大型专科中心的肛门畸形病例、管理和初步结果。方法对 2020 年 11 月至 2021 年 7 月期间在儿科手术室就诊的肛门畸形患儿(15 岁以下)进行为期两年的前瞻性观察研究。结果研究了 61 名患者(男:女=1:0.96)。28.27%的 ARM 是在出生后第一天发现的。超过三分之二的患者(70.5%)是由母亲首次发现的。其余(29.5%)是由医疗专业人员发现的。大多数患者(88.2%)发病较晚(24 小时)。34例(55.4%)病情稳定,20例(32.79%)急性肠梗阻,4例(6.56%)败血症。7名(11.48%)患者伴有先天性畸形。所有患儿都接受了分阶段手术(结肠造口术、PSARP 和结肠造口关闭术)。建立结肠造口与 PSARP 之间的平均持续时间为 7.02 +/- 2.05 个月,而 PSARP 与结肠造口逆转之间的平均持续时间为 8 个月。所有分阶段手术后的并发症发生率和死亡率分别为 39.3% 和 2.2%。5.2%的患者持续大便不畅,3.5%的患者两年后持续便秘。结论:尽管有一些患儿入院较晚且病情不稳定,但ARM患儿的手术治疗效果总体良好。医护人员对ARM的识别较晚,导致患儿就诊时间较晚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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