Delayed return of bowel function after general surgery in South Australia

IF 0.6 Q4 SURGERY
Joshua G. Kovoor , Stephen Bacchi , Brandon Stretton , Aashray K. Gupta , Jonathan Henry W. Jacobsen , Minh-Son To , Rudy Goh , Joseph N. Hewitt , Christopher D. Ovenden , Leigh Warren , Matthew Marshall-Webb , Karen L. Jones , Benjamin A. Reddi , Danny Liew , Christopher Dobbins , Robert T. Padbury , Peter J. Hewett , Thomas J. Hugh , Markus I. Trochsler , Guy J. Maddern
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引用次数: 0

Abstract

Introduction

Reference ranges for determining pathological versus normal postoperative return of bowel function are not well characterised for general surgery patients. This study aimed to characterise time to first postoperative passage of stool after general surgery; determine associations between clinical factors and delayed time to first postoperative stool; and evaluate the association between delay to first postoperative stool and prolonged length of hospital stay.

Methods

This study included consecutive admissions at two tertiary hospitals across a two-year period whom underwent a range of general surgery operations. Multivariable logistic regression analyses were conducted to determine associations between the explanatory variables and delayed first postoperative stool, and between delayed first postoperative stool and length of hospital stay. The previously specified explanatory variables were used, with the addition of the dichotomised ≥4-day delay to first postoperative stool. Prolonged length of hospital stay was considered ≥7 days.

Results

2,212 general surgery patients were included. Median time to first postoperative stool was 2.28 (IQR 1.06–3.96). Median length of stay was 7.19 (IQR 4.50–12.01). Several operative characteristics and medication exposures were associated with delayed first postoperative stool. There was a statistically significant association between delayed first postoperative stool (≥4 days) and prolonged length of stay (≥7 days) (OR 4.34, 95 %CI 3.27 to 5.77, p < 0.001).

Conclusions

This study characterised expected reference ranges for time to return of bowel function across various general surgery operations and determined associations with clinical factors that may improve efficiency and identification of pathology within the postoperative course.

南澳大利亚州普外科手术后肠道功能延迟恢复情况
导言:普外科患者术后肠道功能恢复的病理与正常的参考范围尚未明确。本研究旨在描述普外科术后首次排便时间的特征;确定临床因素与术后首次排便时间延迟之间的关联;评估术后首次排便时间延迟与住院时间延长之间的关联。方法本研究纳入了两家三甲医院在两年内连续收治的接受一系列普外科手术的患者。通过多变量逻辑回归分析确定解释变量与术后首次排便延迟之间的关系,以及术后首次排便延迟与住院时间之间的关系。在使用之前指定的解释变量的基础上,增加了术后首次大便延迟≥4 天的二分变量。住院时间延长被视为≥7天。术后首次排便的中位时间为 2.28(IQR 1.06-3.96)。住院时间中位数为 7.19(IQR 4.50-12.01)。一些手术特征和药物暴露与术后首次排便延迟有关。该研究确定了各种普外科手术肠道功能恢复时间的预期参考范围,并确定了与临床因素的关联,这些临床因素可提高效率并在术后病理过程中进行识别。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
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0.00%
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审稿时长
38 days
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