Alcohol and Heart Failure.

European cardiology Pub Date : 2023-12-26 eCollection Date: 2023-01-01 DOI:10.15420/ecr.2023.12

Debar Rasoul, Ashwin Ajay, Alend Abdullah, Jean Mathew, Benjamin Lee Wei En, Knievel Mashida, Rajiv Sankaranarayanan

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Abstract

Alcohol is the most frequently consumed toxic substance in the world and remains a major global public health issue, with one in three adults consuming it worldwide. Alcohol use is a leading risk factor for disease, contributing to over 60 acute and chronic health conditions, with a particularly complex association with cardiovascular disease. Chronic excessive alcohol consumption is associated with a range of cardiac complications, including decreased myocardial contractility, hypertension, arrhythmias, MI and heart failure. However, low-level alcohol consumption is believed to have a protective effect against ischaemic heart disease and diabetes. In most cohort studies, small to moderate amounts of alcohol consumption have not been linked to heart failure, indicating a threshold effect of alcohol with individual (possibly genetic) predisposition rather than a continuous effect of exposure. This review article explores the potential benefits of alcohol on the heart, the association between alcohol use and alcoholic cardiomyopathy and the epidemiology, clinical correlates and management of alcoholic cardiomyopathy.

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酒精与心力衰竭。

酒精是世界上最常消费的有毒物质，仍然是一个重大的全球公共卫生问题，全世界每三个成年人中就有一个在饮酒。饮酒是导致疾病的主要风险因素，可导致 60 多种急性和慢性疾病，其中与心血管疾病的关系尤为复杂。长期过量饮酒与一系列心脏并发症有关，包括心肌收缩力下降、高血压、心律失常、心肌梗死和心力衰竭。然而，低度饮酒被认为对缺血性心脏病和糖尿病有保护作用。在大多数队列研究中，少量至中等量的饮酒与心力衰竭并无关联，这表明酒精的阈值效应与个体（可能是遗传）倾向有关，而不是暴露的持续效应。这篇综述文章探讨了酒精对心脏的潜在益处、饮酒与酒精性心肌病之间的关联以及酒精性心肌病的流行病学、临床相关性和管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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European cardiology

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