Risk factors for venous thrombosis after esophagectomy.

IF 2.2 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Esophagus Pub Date : 2024-04-01 Epub Date: 2024-01-12 DOI:10.1007/s10388-023-01038-4

Naoya Torii, Kazushi Miyata, Masahide Fukaya, Tomoki Ebata

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引用次数: 0

Abstract

Background: Venous thrombosis (VT) after esophagectomy for esophageal cancer is an important complication, potentially leading to pulmonary embolism. However, there are few available information about the risk for the postsurgical VT.

Methods: This study included 271 patients who underwent esophagectomy for esophageal cancer between 2006 and 2019. Contrast-enhanced computed tomography (CT) was performed for all patients on the seventh postoperative day to survey complications, including VT.

Results: VT was radiologically visualized in 48 patients (17.7%), 8 of whom (16.7%) had pulmonary embolism. The thrombus disappeared in 42 patients, the thrombus size was unchanged in 5 patients, and 1 patient died. Multivariate analysis was performed on factors clinically considered to have a significant influence on thrombus formation. The analysis showed that CVC insertion via the femoral vein (odds ratio, 7.67; 95% CI, 2.64-22.27; P < 0.001), retrosternal reconstruction route (odds ratio, 3.94; 95% CI, 1.90-8.17; P < 0.001) and intraoperative fluid balance < 5 ml/kg/hr (odds ratio, 0.38; 95% CI, 0.17-0.85; P = 0.019) were independently related to VT.

Conclusions: Intraoperative fluid balance < 5 ml/kg/hr, along with CVC insertion via the femoral vein and retrosternal reconstruction may be potential risk factors for VT after esophagectomy.

查看原文本刊更多论文

食管切除术后静脉血栓形成的风险因素。

背景：食管癌食管切除术后静脉血栓形成（VT）是一种重要的并发症，有可能导致肺栓塞。然而，关于术后 VT 风险的信息却很少：本研究纳入了 2006 年至 2019 年期间因食管癌接受食管切除术的 271 名患者。所有患者均在术后第七天进行了对比增强计算机断层扫描（CT），以调查包括VT在内的并发症：48名患者（17.7%）经放射学检查发现VT，其中8名患者（16.7%）出现肺栓塞。42例患者血栓消失，5例患者血栓大小不变，1例患者死亡。对临床认为对血栓形成有重要影响的因素进行了多变量分析。分析结果显示，经股静脉插入 CVC（几率比 7.67；95% CI，2.64-22.27；P 结论：经股静脉插入 CVC 对血栓形成有显著影响：术中液体平衡

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Esophagus GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

4.90

自引率

8.30%

发文量

审稿时长

>12 weeks

期刊介绍： Esophagus, the official journal of the Japan Esophageal Society, introduces practitioners and researchers to significant studies in the fields of benign and malignant diseases of the esophagus. The journal welcomes original articles, review articles, and short articles including technical notes ( How I do it ), which will be peer-reviewed by the editorial board. Letters to the editor are also welcome. Special articles on esophageal diseases will be provided by the editorial board, and proceedings of symposia and workshops will be included in special issues for the Annual Congress of the Society.