Closed-Loop Insulin Delivery May Help Prevent Metabolic Complications During Bariatric Surgery in Patients with Type 1 Diabetes: A Case Report.

IF 5.7 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes technology & therapeutics Pub Date : 2024-04-01 DOI:10.1089/dia.2023.0551

Erika Cornu, Camille Gaulier, Pauline Juttet, Julie Beauvy, Vincent Mezzarobba, Anne-Laure Proust, Jean-Philippe Le Berre, Anne-Cécile Paepegaey

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引用次数: 0

Abstract

Introduction: Obesity in patients with type 1 diabetes (T1D) may worsen their prognosis. Bariatric surgery in these patients can be associated with complications such as diabetic ketoacidosis and severe hypoglycemic episodes. Closed-loop insulin delivery could be a solution to avoid them. Case Report: A 45-year-old woman with T1D and obesity (body mass index of 38.4 kg/m²) was included in our preoperative course of bariatric surgery. Three months before surgery, a closed-loop insulin delivery was instituted due to one prior severe hypoglycemia. Patient did not have immediate or late postoperative hypoglycemia despite consuming a weak amount of carbohydrate. Three months after surgery glycemic control was on target with 86% of time in range 70-180 mg/dL and no time below 70 mg/dL. Conclusion: This case report shows that the use of a closed-loop insulin delivery made it possible to perform bariatric surgery in complete safety for our patient.

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闭环胰岛素输送有助于预防 1 型糖尿病患者在减肥手术期间出现代谢并发症：一份病例报告。

引言1 型糖尿病（T1D）患者肥胖可能会使预后恶化。对这些患者进行减肥手术可能会导致糖尿病酮症酸中毒和严重低血糖等并发症。闭环胰岛素给药可以避免这些并发症：一名患有 T1D 和肥胖症（体重指数为 38.4 kg/m2）的 45 岁女性被纳入了我们的减肥手术术前疗程。术前三个月，由于患者曾发生过一次严重的低血糖，我们对其实施了胰岛素闭环给药。尽管患者摄入了少量碳水化合物，但术后并未出现即刻或晚期低血糖。术后三个月血糖控制达标，86%的时间在 70-180 mg/dl 范围内，没有低于 70 mg/dl 的时间：本病例报告表明，使用闭环胰岛素输送系统可以让患者在完全安全的情况下进行减肥手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes technology & therapeutics 医学-内分泌学与代谢

CiteScore

10.60

自引率

14.80%

发文量

145

审稿时长

3-8 weeks

期刊介绍： Diabetes Technology & Therapeutics is the only peer-reviewed journal providing healthcare professionals with information on new devices, drugs, drug delivery systems, and software for managing patients with diabetes. This leading international journal delivers practical information and comprehensive coverage of cutting-edge technologies and therapeutics in the field, and each issue highlights new pharmacological and device developments to optimize patient care.

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