A fatal septic shock caused by Capnocytophaga gingivalis potentially associated with COVID-19: A case report

IF 1.5 Q2 MEDICINE, GENERAL & INTERNAL

Acute Medicine & Surgery Pub Date : 2024-01-09 DOI:10.1002/ams2.922

Dai Miyazaki, Chika Kunishige, Shigeru Sano, Kahoru Urakawa, Kana Okamoto, Naomi Morishita, Kentaro Iwata

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Abstract

Background

Capnocytophaga spp. is associated with fulminant sepsis, particularly in those with immunosuppression. We here report a rare case of fatal fulminant septic shock caused by C. gingivalis, concurrent with COVID-19.

Case Presentation

A Japanese woman developed septic shock, which led to her death. Polymerase chain reaction (PCR) testing of the respiratory specimen was positive for SARS-CoV-2, and a CT scan of the chests revealed bilateral ground glass opacities. The blood cultures identified C. gingivalis. The patient had rheumatoid arthritis and was taking prednisone orally. There were no splenic abnormalities shown on the CT scan.

Conclusion

A rare case of fulminant septic shock caused by C. gingivalis, together with COVID-19 was identified. The precise pathogenesis of this combination, together with the best treatment option should be sought by further studies.

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可能与 COVID-19 相关的牙龈帽状嗜细胞菌引起的致命脓毒性休克：病例报告

背景噬人牙胞杆菌与暴发性败血症有关，尤其是在免疫抑制患者中。我们在此报告一例罕见的由牙龈噬菌体引起的致命性脓毒性休克病例，该病例同时感染了 COVID-19。病例介绍一名日本女性出现脓毒性休克并最终死亡。呼吸道标本的聚合酶链反应（PCR）检测显示 SARS-CoV-2 阳性，胸部 CT 扫描显示双侧磨玻璃不透明。血液培养发现了牙龈球菌。患者患有类风湿性关节炎，正在口服强的松。CT 扫描未发现脾脏异常。结论发现了一例罕见的由牙龈裂头蚴和 COVID-19 共同引起的暴发性脓毒性休克病例。应通过进一步的研究来探究这种合并症的确切发病机制以及最佳治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acute Medicine & Surgery MEDICINE, GENERAL & INTERNAL-

自引率

12.50%

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审稿时长

53 weeks