Insight into the treatment strategy on pneumonia transmission with asymptotic carrier stage using fractional order modeling approach

Shewafera Wondimagegnhu Teklu , Belela Samuel Kotola
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Abstract

Pneumonia remains a significant global health concern, claiming millions of lives annually. This study introduces a novel approach by developing and analyzing a Caputo fractional order pneumonia infection model that incorporates pneumonia asymptomatic carriers. Through a qualitative lens, we establish the existence and uniqueness of model solutions by applying the well-known Picard–Lindelöf criteria. Employing a next-generation approach, we compute the model's basic reproduction number, determine equilibrium points, and probe their stabilities. The main objective of this study is to investigate the transmission dynamics of pneumonia infection with a focus on asymptomatic carriers using fractional order modeling. Our findings reveal innovative outcomes as we showcase numerical simulations, providing a practical verification of the qualitative results. Notably, we explore the fractional order model solutions in-depth, examining the influence of specific model parameters and fractional orders on the dynamics of pneumonia disease transmission. The significant contributions of this study lie in advancing the theoretical foundation of infectious disease modeling, particularly in the context of pneumonia. Through rigorous analysis and numerical simulations, we provide valuable insights into the behavior of the proposed fractional order model. These findings hold practical implications for understanding and managing pneumonia transmission in real-world scenarios. Our study serves as a vital resource for researchers, policymakers, and healthcare practitioners involved in combating and preventing the spread of pneumonia, ultimately contributing to global efforts in public health.

利用分数阶建模方法洞察渐进载体阶段肺炎传播的治疗策略
肺炎仍然是全球关注的重大健康问题,每年夺走数百万人的生命。本研究通过开发和分析包含肺炎无症状携带者的卡普托分数阶肺炎感染模型,引入了一种新方法。通过定性视角,我们应用著名的 Picard-Lindelöf 准则确定了模型解的存在性和唯一性。采用新一代方法,我们计算了模型的基本繁殖数,确定了平衡点,并探究了其稳定性。本研究的主要目的是利用分数阶模型研究肺炎感染的传播动态,重点是无症状带菌者。通过展示数值模拟,我们的研究结果揭示了创新成果,为定性结果提供了实际验证。值得注意的是,我们深入探讨了分数阶模型解,研究了特定模型参数和分数阶对肺炎疾病传播动态的影响。本研究的重大贡献在于推进了传染病建模的理论基础,特别是在肺炎的背景下。通过严格的分析和数值模拟,我们对所提出的分数阶模型的行为提供了有价值的见解。这些发现对于理解和管理现实世界中的肺炎传播具有实际意义。我们的研究为研究人员、政策制定者以及参与抗击和预防肺炎传播的医疗从业人员提供了重要资源,最终将为全球公共卫生事业做出贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
5.90
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