The Theoretical Description for Cenobamate CuS-Assisted Electrochemical Determination in Pharmaceutical Formulations and Wastewater

IF 0.7 Q4 CHEMISTRY, MULTIDISCIPLINARY

Orbital: The Electronic Journal of Chemistry Pub Date : 2024-01-03 DOI:10.17807/orbital.v15i4.19558

Volodymyr Tkach, Tetiana Morozova, V. Khrutba, Andrii Hlukhonets, Marta Kushnir, Y. Ivanushko, Viktor Kryvetskyi, Inna Kryvetska, I. Kryvetskyi, P. Yagodynets, M. Kucher, Z. Kormosh, Nadiia Chikun, Maria João Monteiro

引用次数: 0

Abstract

For the first time, the theoretical description for cenobamate antiepileptic drug on anode, assisted by copper sulfide nanoparticles in alkaline medium, has been given. Two mechanisms, involving either tetrazolic ring, or the carbocyclic aromatic moiety, are possible for this process, reason why the concentration of the drug will be identified and quantified by two peaks. Despite of the mechanism hybrid nature, both of the peaks will produce an easy interpretable analytical signal, being thereby possible to confirm the efficiency of the electroanalytical signal.

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药物制剂和废水中氯钴胺 CuS 辅助电化学检测的理论描述

该研究首次从理论上描述了在碱性介质中硫化铜纳米粒子的辅助下，阳极上的仙诺巴马特抗癫痫药物。这一过程可能涉及四氮唑环或碳环芳香分子的两种机制，因此药物浓度将通过两个峰值来识别和量化。尽管机制是混合的，但这两个峰都会产生易于解释的分析信号，从而可以确认电分析信号的效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Orbital: The Electronic Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： Orbital: The Electronic Journal of Chemistry is a quarterly scientific journal published by the Institute of Chemistry of the Universidade Federal de Mato Grosso do Sul, Brazil. Original contributions (in English) are welcome, which focus on all areas of Chemistry and their interfaces with Pharmacy, Biology, and Physics. Neither authors nor readers have to pay fees. The journal has an editorial team of scientists drawn from regions throughout Brazil and world, ensuring high standards for the texts published. The following categories are available for contributions: 1. Full papers 2. Reviews 3. Papers on Education 4. History of Chemistry 5. Short communications 6. Technical notes 7. Letters to the Editor The Orbital journal also publishes a number of special issues in addition to the regular ones. The central objectives of Orbital are threefold: (i) to provide the general scientific community (at regional, Brazilian, and worldwide levels) with a formal channel for the communication and dissemination of the Chemistry-related literature output by publishing original papers based on solid research and by reporting contributions which further knowledge in the field; (ii) to provide the community with open, free access to the full content of the journal, and (iii) to constitute a valuable channel for the dissemination of Chemistry-related investigations.