Evaluation of mercury in skin lightening creams commonly used in Trinidad and Tobago and their associated health risk

Terry Mohammed, Nadira Rambocas, Sanjeev Basdeo, Yasphal Kissoon
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Abstract

Objectives: This study investigated the presence of mercury in commonly used over the counter skin-lightening creams available in Trinidad and Tobago. The objective of this study was to evaluate if skin-lightening creams commonly used in Trinidad and Tobago contained Mercury, and establish the health risks presented by these products. Methods: Nineteen skin-lightening creams were analysed using Cold Capor Atomic Absorption Spectrophotometry (CV-AAS). Margin of Safety (MoS) and Hazard Quotient (HQ) calculations were used to assess risk to users. Results: Of the nineteen creams assessed, sixteen contained high concentrations of mercury (0.294-14414.5 µg/g), only three creams had no mercury detected. 9 of the 19 samples contained levels of mercury that exceed the Minamata convention’s accepted limit of 1µg/g, with 3 samples exceeding 3800.000 µg/g. Risk assessments using MoS and HQ showed that 3 of the samples were unsafe for use and are considered hazardous. The study also revealed that many creams do contain mercury even if it did not constitute part of the product formulation. Conclusions: The data infers that some manufacturers do add mercury to their formulations while others are the victims of contaminated raw materials. MoS and HQ show that 21% of the samples were unsafe and 16% can be considered hazardous for human use. It is possible that with such levels of mercury in these products and the popularity of these products within the Caribbean Community and its diaspora, that there exists a significant amount of members with higher than acceptable mercury levels, with undiagnosed clinical symptoms.
评估特立尼达和多巴哥常用美白霜中的汞及其相关健康风险
研究目的本研究调查了特立尼达和多巴哥常用的非处方美白霜中是否含有汞。本研究的目的是评估特立尼达和多巴哥常用的美白霜中是否含有汞,并确定这些产品对健康造成的风险。研究方法使用 Cold Capor 原子吸收分光光度法(CV-AAS)对 19 种美白霜进行了分析。使用安全系数 (MoS) 和危害商数 (HQ) 计算来评估使用者面临的风险。结果:在被评估的 19 种面霜中,有 16 种含有高浓度的汞(0.294-14414.5 微克/克),只有 3 种面霜未检测到汞。19 个样品中有 9 个样品的汞含量超过了《水俣公约》规定的 1 微克/克的公认限值,其中 3 个样品的汞含量超过了 3800.000 微克/克。使用 MoS 和 HQ 进行的风险评估显示,其中 3 个样本的使用不安全,被认为是有害的。研究还显示,许多面霜确实含有汞,即使汞不是产品配方的一部分。结论:数据推断,一些生产商确实在配方中添加了汞,而另一些生产商则是原材料受污染的受害者。MoS 和 HQ 显示,21% 的样品不安全,16% 的样品可被视为对人体有害。由于这些产品中的汞含量如此之高,加之这些产品在加勒比共同体及其侨民中很受欢迎,因此可能有 大量成员的汞含量高于可接受水平,并伴有未确诊的临床症状。
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