Investigating the Association between Blood Transfusion and Hepatitis C infection During Pregnancy

Pakistan Journal of Medical and Health Sciences Pub Date : 2023-06-30 DOI:10.53350/pjmhs2023176372

A. Naz, Yasmeen Rasheed Bhutto, Kiran Memon, A. Bhutto, Rukhsana Saboor, Durgha Devi, Aamir Ramzan, Kiran Aamir

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Abstract

Objective: Aim was determine the association between blood transfusion and hepatitis C infection during pregnancy. Study Design: Descriptive study Place and Duration: Peoples University of Medical and Health Sciences Nawabshah. Feb 2021-Jan 2022 Methods: Total 171 pregnant women of age 18-40 years were presented in this study. The patient's age, parity, and other risk factors such as previous operations, vaginal births, and transfusions were recorded, and a thorough physical examination was conducted. Anti HCV positivity on Immunochromatography Test (ICT) was confirmed by Elisa in patients undergoing normal prenatal evaluation. The data collection process followed a carefully crafted proforma. To examine the information, we used SPSS 22.0. Results: Among 171 patients, 82 (47.95%) females had age 18-25 years, 57 (33.3%) patients had age 26-35 years and 32 (18.7%) females had age 36-40 years. 75 (43.6%) cases had BMI >25kg/m2. 49 (28.7%) cases were primigravida and rest 120 (71.3%) cases were multi-gravida. We found 15 (8.8%) cases of HCV positive. Among 15 cases, 8 cases had history of blood transfusion, 3 had history of surgery, 2 cases because of injections and 2 cases had jaundice. Among 15 positive cases, majority of the cases had age 26-35 years. Conclusion: We found in this that blood transfusion is a significantly risk factor for HCV among pregnant females. There is need to educated pregnant females at institution to avoid its prevalence during pregnancy. Keywords: Pregnant Females, Blood transfusion, HCV, Parity

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调查孕期输血与丙型肝炎感染之间的关系

目的旨在确定孕期输血与丙型肝炎感染之间的关联。研究设计：描述性研究地点和时间纳瓦布沙赫人民医科大学（Peoples University of Medical and Health Sciences Nawabshah）。2021 年 2 月至 2022 年 1 月方法：对 171 名年龄在 18 岁至 40 岁之间的孕妇进行调查：共有 171 名 18-40 岁的孕妇参与了这项研究。研究人员记录了患者的年龄、胎次和其他风险因素，如既往手术、阴道分娩和输血，并进行了全面的身体检查。在接受正常产前评估的患者中，免疫层析检测（ICT）证实抗 HCV 阳性。数据收集过程遵循精心制作的表格。我们使用 SPSS 22.0 对信息进行了检验。结果：在 171 名患者中，82 名（47.95%）女性患者的年龄在 18-25 岁之间，57 名（33.3%）患者的年龄在 26-35 岁之间，32 名（18.7%）女性患者的年龄在 36-40 岁之间。75（43.6%）例患者的体重指数大于 25kg/m2。49例（28.7%）为初产妇，其余120例（71.3%）为多产妇。我们发现 15 例（8.8%）HCV 阳性。在 15 例中，8 例有输血史，3 例有手术史，2 例因为注射，2 例有黄疸。在 15 例阳性病例中，大多数病例的年龄在 26-35 岁之间。结论我们发现输血是孕妇感染丙型肝炎病毒的一个重要风险因素。有必要在医疗机构对孕妇进行教育，以避免其在怀孕期间感染。关键词孕妇输血 HCV 胎次

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Pakistan Journal of Medical and Health Sciences

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