Recent Update on Topical Drug Delivery Systems: Emulgel

Kajal T. Lilhare, S. Borkar, Jagdish R. Baheti
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Abstract

Emulgel is an emerging topical drug delivery system that, if more effort is devoted to its formulation and development with more topically active drugs, will prove to be a boon to skin care and cosmetology. Emulgels are both O/W or W/O emulsions which might be gelled with the aid of mixing with a gelling agent. Incorporating the emulgel increases its stability and makes it controlled release system. Due to the lack of excess oil bases and insoluble excipients, it exhibits better drug release compared to other topical drug delivery systems. The presence of the gel phase makes it non-greasy and promotes good affected person cooperation. Those reviews provide knowledge approximately Emulgel such as its properties, benefits, formulations and its current research advances. All elements consisting of the choice of gelling agent, oil agent, emulsifiers affecting the stability and effectiveness of Emulgel are discussed. All rationales are defined in accordance with study conducted via numerous scientists. After anin depth examine, it could be concluded that Emulgels appear to be a better and greater  effective drug delivery system compared to other topical drug delivery systems. A complete analysis of the rheological and release properties will offer insight into the capacity  use of the Emulgel formulation as a drug delivery System.
局部给药系统的最新进展:凝胶剂
润肤凝胶是一种新兴的局部给药系统,如果在其配制和开发方面投入更多精力,并使用更多局部活性药物,那么它将被证明是皮肤护理和美容业的福音。润肤凝胶是一种水包油型或油包水型乳液,可借助与胶凝剂的混合而凝胶化。加入胶凝剂可增加其稳定性,并使其成为控释系统。由于不含过量的油基和不溶性辅料,与其他局部给药系统相比,它能更好地释放药物。凝胶相的存在使其不油腻,促进了患者的良好配合。这些评论提供了有关 Emulgel 的知识,如其特性、益处、配方及其当前的研究进展。讨论了影响 Emulgel 稳定性和有效性的所有因素,包括胶凝剂、油剂、乳化剂的选择。所有理论依据都是根据众多科学家的研究确定的。经过深入研究,可以得出结论:与其他外用给药系统相比,Emulgels 似乎是一种更好、更有效的给药系统。对流变和释放特性的全面分析将有助于深入了解作为给药系统的 Emulgel 配方的使用能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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