Biological reduction of aflatoxin M1 in dairy products using probiotic strains: a systematic review and meta-analysis

IF 1.7 4区医学 Q3 FOOD SCIENCE & TECHNOLOGY

World Mycotoxin Journal Pub Date : 2023-09-25 DOI:10.1163/18750796-20212761

L. Monjazeb Marvdashti, A. Emadi, M. Eslami, B. Yousefi, M. Arabameri, A. Abdolshahi, N. Shariatifar

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引用次数: 0

Abstract

Aflatoxins are naturally occurring toxic substances produced mainly by species of the genus Aspergillus that can contaminate almost all foodstuffs. Apart from the harmful effects they have on human and animal health, they can be secreted unchanged in animal milk and cause contamination of milk and its products. Aflatoxin M1 (AFM1) is the major and most toxic type of aflatoxin after aflatoxin B1 (AFB1). The use of probiotic strains to reduce the amount of aflatoxin in milk and by-products has been observed in many studies. In this systematic review and meta-analysis, articles in PubMed, Scopus, Google Scholar and ISI Web of Science were searched to find eligible studies that reported reduction of AFM1 using probiotics in dairy products. The results were pooled using a random-effects model. In most studies, the efficiency of probiotics in milk has been tested by Lactobacillus strains. The results indicated that probiotic microorganisms could significantly reduce AFM1 by 55.76% (confidence interval (CI): 54.35%, 57.16%; I2 = 100%). Besides, the rank order of AFM1 reduction in dairy products based on probiotic strain subgroup was: Lactobacillus 51.99% (CI: 50.14%, 53.85%, I2 = 100%), Saccharomyces 67.36% (CI: 65.05%, 69.67%, I2 = 100%), Bifidobacterium 54.80% (CI: 54.18%, 55.43%, I2 = 99.9%), and 61.90% (CI: 53.80%, 70.00%, I2 = 100%) by a mix of strains. Considering the high binding potential of AFM1 to probiotic strains, these microorganisms can be recommended as a safe system to reduce AFM1 in dairy products.

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利用益生菌菌株从生物学角度减少乳制品中的黄曲霉毒素 M1：系统综述和荟萃分析

黄曲霉毒素是一种天然的有毒物质，主要由曲霉属的菌种产生，几乎可以污染所有食品。黄曲霉毒素除了对人类和动物的健康造成危害外，还可以不经改变地分泌到动物乳汁中，造成乳汁及其产品的污染。黄曲霉毒素 M1（AFM1）是仅次于黄曲霉毒素 B1（AFB1）的主要和毒性最强的黄曲霉毒素。许多研究发现，使用益生菌株可以减少牛奶和副产品中的黄曲霉毒素含量。在本系统综述和荟萃分析中，我们搜索了 PubMed、Scopus、Google Scholar 和 ISI Web of Science 中的文章，以找到符合条件的、报道使用益生菌降低乳制品中 AFM1 含量的研究。研究结果采用随机效应模型进行了汇总。在大多数研究中，牛奶中益生菌的效率都是通过乳酸杆菌菌株来测试的。结果表明，益生微生物可显著降低 AFM1 55.76%（置信区间（CI）：54.35%，57.16%；I2 = 100%）。此外，根据益生菌菌株亚群，乳制品中 AFM1 减少量的排名顺序为乳酸杆菌为 51.99%（CI：50.14%，53.85%，I2 = 100%），酵母菌为 67.36%（CI：65.05%，69.67%，I2 = 100%），双歧杆菌为 54.80%（CI：54.18%，55.43%，I2 = 99.9%），混合菌株为 61.90%（CI：53.80%，70.00%，I2 = 100%）。考虑到 AFM1 与益生菌株的高结合潜力，这些微生物可被推荐为减少乳制品中 AFM1 的安全系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Mycotoxin Journal MYCOLOGY-

CiteScore

4.60

自引率

5.00%

发文量

审稿时长

>12 weeks

期刊介绍： ''World Mycotoxin Journal'' is a peer-reviewed scientific journal with only one specific area of focus: the promotion of the science of mycotoxins. The journal contains original research papers and critical reviews in all areas dealing with mycotoxins, together with opinions, a calendar of forthcoming mycotoxin-related events and book reviews. The journal takes a multidisciplinary approach, and it focuses on a broad spectrum of issues, including toxicology, risk assessment, worldwide occurrence, modelling and prediction of toxin formation, genomics, molecular biology for control of mycotoxigenic fungi, pre-and post-harvest prevention and control, sampling, analytical methodology and quality assurance, food technology, economics and regulatory issues. ''World Mycotoxin Journal'' is intended to serve the needs of researchers and professionals from the scientific community and industry, as well as of policy makers and regulators.