Association between Torque Teno Virus Frequency and Systemic Lupus Erythematosus: A Potential Trigger for Autoimmune Diseases

Abstract

A significant correlation was found between SLE and the presence of TTV ( r = .32, p = .03). There was no correlation between the presence of TTV and musculoskeletal involvements, skin lesions, renal manifestations, and hematological manifestations ( r < .05, p > .05). TTV was detected more frequently in patients with active lupus than in patients with quiescent disease, and this difference was significant ( p = .048). Conclusion : A significant association between TTV and SLE was observed in the present study; however, further studies are needed to investigate the role of TTV in the pathogenesis and clinical course of SLE.