Adherence to antibiotics among adults at state sector primary care in a district of Sri Lanka – a descriptive cross sectional study

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
Shalinie Nirma Malintha, Prasanna Siriwardena, M. Weerasinghe
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Abstract

Objectives: To assess the adherence and factors associated with oral antibiotic prescriptions among adults in state sector primary care while assessing the intention to use leftover antibiotics (LOAB).Methodology: A descriptive cross sectional study was conducted in outpatient departments including 407 adults (18-75) using an interviewer administered questionnaire at consultation and a telephone interview at due completion of antibiotic. Adherence was measured by a self-report supplemented by remaining pill count. Factors associated with adherence were determined. The statistical significance was considered as p≤0.05.Results: Adherence to antibiotic prescription was 45.5%. Female gender (p=0.029, OR=1.86) and awareness on the current antibiotic prescription (p=0.000, OR=6.37) were positive associations. Adherence was inversely proportionate to increasing daily dosage frequency (p=0.001). Patient’s belief, they can stop medicine once they feel better (p=0.000), fast improvement of symptoms with medication (p=0.000), interference to lifestyle by the antibiotic dosage schedule (p=0.000) and using LOAB in the past (p=0.000,) were negatively associated. Of the non-adherent patients 20.3% intended to use LOAB later.Conclusions: Adherence to oral antibiotic prescriptions was poor. Patient’s gender, patient beliefs and practices towards medicine and complexity of dosage schedule were associated factors. Patient awareness on the current prescription promoted adherence. Intension to use LOAB was high.Recommendations: Primary care prescribers should make patients aware on antibiotic prescriptions while using less complex regimens.
斯里兰卡某地区国营初级保健机构成人抗生素使用情况--一项描述性横断面研究
目的评估国营基层医疗机构成人口服抗生素处方的依从性及相关因素,同时评估使用剩余抗生素(LOAB)的意向:在门诊部进行了一项描述性横断面研究,包括 407 名成人(18-75 岁),在就诊时使用访问者发放的问卷,并在抗生素用完时进行电话访问。依从性是通过自我报告并辅以剩余药片计数来衡量的。确定了与依从性相关的因素。统计学意义以 p≤0.05 为准:结果:抗生素处方的依从性为 45.5%。女性(p=0.029,OR=1.86)和对当前抗生素处方的认识(p=0.000,OR=6.37)呈正相关。依从性与每日用药次数的增加成反比(p=0.001)。患者认为一旦感觉好转就可以停药(p=0.000)、用药后症状改善快(p=0.000)、抗生素剂量表对生活方式的干扰(p=0.000)和过去使用过 LOAB(p=0.000)则呈负相关。在非依从性患者中,20.3%的人打算以后使用LOAB:结论:口服抗生素处方的依从性很差。结论:口服抗生素处方的依从性很差,与患者的性别、患者对药物的信仰和习惯以及剂量表的复杂性有关。患者对当前处方的认识促进了对处方的依从性。使用 LOAB 的意愿很高:建议:初级保健处方者应让患者了解抗生素处方,同时采用不太复杂的治疗方案。
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来源期刊
Ceylon Medical Journal
Ceylon Medical Journal MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
16
期刊介绍: The Ceylon Medical Journal, is the oldest surviving medical journal in Australasia. It is the only medical journal in Sri Lanka that is listed in the Index Medicus. The CMJ started life way back in 1887 as the organ of the Ceylon Branch of the British Medical Association. Except for a brief period between 1893 and 1904 when it ceased publication, the CMJ or its forbear, the Journal of the Ceylon Branch of the British Medical Association, has been published without interruption up to now. The journal"s name changed to the CMJ in 1954.
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