ROLE OF KATHAKAKHADIRADI KASHAYA IN PREVENTIVE DIABETOLOGY; A CASE REPORT

Abstract

Diabetes mellitus is an abnormal scenario of altered glucose tolerance due to inadequate insulin action. Small blood vessels are susceptible to the complications of diabetes mellitus, such as basal lamina thickening and endothelial cell proliferation called diabetic microangiopathy, frequently causing retinal and renal damage. Microangiopathy affecting the kidney is called diabetic nephropathy and is the second leading cause of death due to diabetes mellitus after myocardial infarction. Due to the persistent hyperglycemic status of microcapillaries in the kidney, some histological changes occur in the nephron level detected by electron microscopy only after a few years of onset of diabetes [1]. This is a case report of a known diabetic and hypertensive patient who complained of frothy urine and was diagnosed as type 2 diabetes-induced microalbuminuria and intervened with Kathaka Khadiradi Kashaya, a traditional antidiabetic formulation famous in South India. Two months of administration of the medicine reduced the urine microalbumin and albumin creatinine ratio to a significant normalcy, hence proved to be a choice for a clinical trial in the preventive aspect of diabetic nephropathy.