Molecular Detection of Metallo-Beta Lactamases Among Carbapenem-Resistant Pseudomonas aeruginosa Isolated From Patients With Burn in Baghdad City, Iraq

Hadeel Kazem, Samer Muhammad
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Abstract

to examine the prevalence of MBL-producing Pseudomonas aeruginosa in burn and non-burn patients, 68 Pseudomonas aeruginosa isolates were collected from different clinical sources from two hospitals in Baghdad. Antibiotic susceptibility tests were PCR performed on carbapenem-resistant isolates, Among the Pseudomonas aeruginosa isolates, 50% were meropenem and 39% were imipenem, Among all Pseudomonas aeruginosa isolates, 63.23% were multidrug-resistant and 51.5% were resistant to carbapenems (meropenem and imipenem), It has been determined blaVIM, blaSPM and blaNDM in 22.9%, 2.9% and 5.7% respectively blaIMP were not observed. For the efficient treatment of carbapenem-resistant P. aeruginosa infections, epidemiological and geographic evaluation of MBL-producing P. aeruginosa should be taken into consideration.
从伊拉克巴格达市烧伤患者中分离出的耐碳青霉烯类铜绿假单胞菌中进行金属β内酰胺酶分子检测
为研究烧伤和非烧伤患者中产 MBL 铜绿假单胞菌的流行情况,从巴格达两家医院的不同临床来源收集了 68 个铜绿假单胞菌分离株。在所有铜绿假单胞菌分离株中,63.23%对多种药物耐药,51.5%对碳青霉烯类(美罗培南和亚胺培南)耐药。为有效治疗对碳青霉烯类耐药的铜绿假单胞菌感染,应考虑对产生 MBL 的铜绿假单胞菌进行流行病学和地理学评估。
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