Topical Lidocaine Gel Versus Tetracaine Eye Drops for Panretinal Photo-coagulation in Proliferative Diabetic Retinopathy

Medical Scope Journal Pub Date : 2023-11-26 DOI:10.35790/msj.v6i1.51380

A. Nursalim, Vera Sumual, Andrew Chietra, C. Komaling, S. Loho, Ardelia E. Wulur

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Abstract

Panretinal photocoagulation (PRP) is a treatment for proliferative diabetic retinopathy (PDR). The procedure needs anesthetic agent to overcome the pain. Two widely used anesthetic agents are used in this study which are tetracaine 0.5% eyedrops and lidocaine 2% gel. This study aimed to compare the effectivity and efficacy of both anesthetic agents. A prospective randomized controlled trial was done to 40 eyes divided into two groups, group A was treated with tetracaine 0.5% eyedrop and group B with lidocaine 2% gel. Pain score was obtained subjectively from the patient and recorded during four stages of procedure. The results showed that the mean age was 56.5 years in Group A and 53.20 years in group B. Average procedure duration was 8.7 minutes in group A and 9.35 minutes in group B. Average 5 minutes pain level was 3.05 and 2.10 in group A and B consecutively. Average 10 minutes pain level was 2.65 and 2.45 in group A and B consecutively. Average during procedure pain level was 2.70 and 3.40 in group A and Group B, and average post procedure pain level was 1.20 in Group A and 1.55 in Group B. There was no significant difference between both groups’ parameters. In conclusion, the use of both agents is interchangeable and shows no differences in efficacy and effectivity. Keywords: panretinal photocoagulation; proliferative diabetic retinopathy; anesthetic agent; tetracaine; lidocaine

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局部利多卡因凝胶与四乙卡因滴眼液在增殖性糖尿病视网膜病变中的全视网膜光凝治疗效果比较

全视网膜光凝术（PRP）是一种治疗增殖性糖尿病视网膜病变（PDR）的方法。手术需要麻醉剂来克服疼痛。本研究使用了两种广泛使用的麻醉剂，即 0.5% 四卡因眼药水和 2% 利多卡因凝胶。本研究旨在比较两种麻醉剂的作用和疗效。研究采用前瞻性随机对照试验方法，将 40 只眼睛分为两组，A 组使用 0.5% 四卡因眼药水，B 组使用 2% 利多卡因凝胶。疼痛评分由患者主观获得，并在手术的四个阶段进行记录。结果显示，A 组患者的平均年龄为 56.5 岁，B 组患者的平均年龄为 53.20 岁；A 组患者的平均手术时间为 8.7 分钟，B 组患者的平均手术时间为 9.35 分钟；A 组和 B 组患者的平均 5 分钟疼痛程度分别为 3.05 和 2.10。A 组和 B 组连续 10 分钟的平均疼痛程度分别为 2.65 和 2.45。A 组和 B 组术中平均疼痛程度分别为 2.70 和 3.40，术后平均疼痛程度分别为 1.20 和 1.55。总之，两种药物可以互换使用，在疗效和有效性方面没有差异。关键词：全视网膜光凝术；增殖性糖尿病视网膜病变；麻醉剂；四卡因；利多卡因

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Medical Scope Journal

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