Formulation And Physical Stability Test Of Mother-In-Law’s Tongue Leaves Extract Lotion As An Antioxidant

L. M. Yuningsih, Dikdik Mulyadi, Siti Inayah, Sita Sopatul Marwah
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Abstract

Mother-in-law's tongue leaves (Sansevieria trifasciata P.) is a plant of the genus Sansevieria with flavonoid compound namely trifasciatin, as an antioxidant. Antioxidants can be used in cosmetics to protect the skin from free radicals. The purpose of this research was to analyze antioxidant activity of mother-in-law's tongue leaves extract and to obtain the best lotion formulation with various concentrations. Samples were extracted using 96% ethanol solvent with maceration method. Antioxidant activity was tested using DPPH method and intensity was measured at λ=517 nm by UV-Vis spectrophotometer. The IC50 value=49.72 ppm indicates a very strong antioxidant activity, compared to vitamin C=4.01 ppm (very strong). Extract was formulated in lotion with various concentrations of 0.5%, 1%, 3%, 6% and the comparison was vitamin C with same concentration as well as base without the addition of active substances. Based on observations for 4 weeks, 3% extract lotion is the best formulation. The organoleptic test results showed no change in shape, texture, color, odor, and pH so lotion was stable. In addition, the value of viscosity, spreadability, adhesion, irritation test according to established standards also has an antioxidant value  99.72% (strong category). So effective to ward off free radicals on the skin.
岳母舌叶提取物乳液作为抗氧化剂的配方和物理稳定性测试
岳母舌叶(Sansevieria trifasciata P.)是一种含黄酮类化合物(即 trifasciatin)的桑科植物,是一种抗氧化剂。抗氧化剂可用于化妆品,保护皮肤免受自由基的伤害。本研究的目的是分析岳母舌叶提取物的抗氧化活性,并获得不同浓度的最佳乳液配方。样品使用 96% 的乙醇溶剂浸泡法提取。采用 DPPH 法测试抗氧化活性,并用紫外可见分光光度计在 λ=517 纳米处测量强度。与维生素 C=4.01 ppm(非常强)相比,IC50 值=49.72 ppm 表明其抗氧化活性非常强。将提取物配制成 0.5%、1%、3%、6% 等不同浓度的乳液,并与相同浓度的维生素 C 和未添加活性物质的基质进行比较。根据 4 周的观察,3% 的提取物乳液是最佳配方。感官测试结果表明,乳液的形状、质地、颜色、气味和 pH 值均无变化,因此乳液是稳定的。此外,按照既定标准进行的粘度、涂抹性、粘附性、刺激性测试值也达到了抗氧化值 99.72%(强效类)。因此能有效抵御皮肤上的自由基。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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