Dengue Fever Presenting with Concomitant Acute Coronary Syndrome (ACS) - A Series of 5 Cases At A Tertiary Care Hospital In Dhaka

Journal of Bangladesh College of Physicians and Surgeons Pub Date : 2023-11-28 DOI:10.3329/jbcps.v41i40.69713

Tazin Afrose Shah, Umme Salma Khan, Md Farhan Matin, Tanjina Darain Allin, Bryan M Khongwar Nongsiej

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Abstract

Dengue fever may present with many cardiovascular manifestations contributing to death and disability. Acute Coronary Syndrome (ACS) during dengue is rare but poses important management dilemma. Here we present a series of 5 patients with dengue fever who developed different types of ACS during the ongoing dengue endemic in Bangladesh. Five patients admitted with dengue fever and who developed ACS between 1st July to 30th September 2023 at Medicine Department of Uttara Adhunik Medical College, Dhaka, Bangladesh were studied. All the patients had some co[1]morbidity like diabetes, hypertension, or both. Treatment of ACS was tailored according to their CBC report, most importantly, platelet count, and hematocrit. Four out of the 5 patients responded well to anti-ischemic therapy, even though anti-platelet and anti-coagulants could not be given in all cases. There was 1 fatality, but that was due to ARDS consequent due to severe bilateral pneumonia. Management of ACS in dengue is challenging. Physicians should have appropriate preparedness to deal with these cases. J Bangladesh Coll Phys Surg 2023; 41: 82-87

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登革热并发急性冠状动脉综合征（ACS）--达卡一家三级医院的 5 例系列病例

登革热可能会出现多种心血管表现，导致死亡和残疾。登革热期间的急性冠状动脉综合征（ACS）非常罕见，但却造成了重要的管理难题。在此，我们介绍了在孟加拉国登革热流行期间发生不同类型急性冠状动脉综合征的 5 例登革热患者。研究对象为孟加拉国达卡 Uttara Adhunik 医学院医学系收治的五名登革热患者，他们在 2023 年 7 月 1 日至 9 月 30 日期间发生了急性冠状动脉综合征。所有患者都患有糖尿病、高血压等并发症[1]，或同时患有这两种疾病。根据他们的全血细胞计数报告，最重要的是血小板计数和血细胞比容，为他们量身定制了 ACS 治疗方案。5 名患者中有 4 人对抗缺血治疗反应良好，尽管不能在所有病例中都使用抗血小板和抗凝血剂。有 1 人死亡，但死因是严重的双侧肺炎导致的急性呼吸衰竭。登革热急性呼吸系统综合征的治疗具有挑战性。医生应做好应对这些病例的适当准备。J Bangladesh Coll Phys Surg 2023; 41: 82-87

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Journal of Bangladesh College of Physicians and Surgeons

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