Copper Oxide Nanoparticles Synthesized from Indigofera linnaei Ali and This Plant’s Biological Applications

IF 3.1 4区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Inorganics Pub Date : 2023-11-28 DOI:10.3390/inorganics11120462

Nadarajan Prathap, Nagarajan Dravid, Srinivasan R. Kaarmukhilnilavan, M. Shivakumar, S. Venkatesan, M. Shaik, Baji Shaik

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引用次数: 0

Abstract

The leaf extract of Indigofera linnaei Ali, an Indian medicinal plant, was utilized in the synthesis of copper oxide nanoparticles (CuO-NPs). Green chemistry is a safe and cost-effective method for the synthesis of nanoparticles using plant extracts. The synthesis of CuO NPs was confirmed using ultraviolet–visible (UV-visible) spectrum λ-max data with two peaks at 269 and 337 nm. Different functional groups were identified using Fourier-transform infrared spectroscopy (FT-IR). X-ray diffraction (XRD) was used to confirm the crystalline structure of the CuO-nanoparticles. Scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) analyses were performed to examine the surface morphology and elemental composition of the biosynthesized CuO-NPs. Furthermore, the synthesized CuO-NPs exhibited antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Enterococcus faecalis. Additionally, they exhibited a good insecticidal effect on Culex quinquefasciatus larvae, with low LC50 55.716 µg/mL and LC90 123.657 µg/mL values. The CuO-NPs inhibited human breast cancer cells in a concentration-dependent manner, with an IC50 value of 63.13 µg/mL.

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阿里靛蓝合成的纳米氧化铜及其生物应用

印度药用植物 Indigofera linnaei Ali 的叶提取物被用于合成纳米氧化铜颗粒（CuO-NPs）。绿色化学是利用植物提取物合成纳米粒子的一种安全、经济的方法。利用紫外可见光谱（UV-visible）λ-max 数据确认了 CuO NPs 的合成，在 269 纳米和 337 纳米处有两个峰。利用傅立叶变换红外光谱（FT-IR）确定了不同的官能团。X 射线衍射 (XRD) 被用来确认 CuO 纳米粒子的晶体结构。扫描电子显微镜（SEM）和能量色散 X 射线（EDX）分析用于研究生物合成的 CuO-NPs 的表面形态和元素组成。此外，合成的 CuO-NPs 对金黄色葡萄球菌、绿脓杆菌、大肠杆菌和粪肠球菌具有抗菌活性。此外，它们还对五带喙库蚊幼虫具有良好的杀虫效果，半数致死浓度为 55.716 微克/毫升，半数致死浓度为 123.657 微克/毫升。CuO-NPs 以浓度依赖的方式抑制人类乳腺癌细胞，其 IC50 值为 63.13 µg/mL。

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来源期刊

Inorganics Chemistry-Inorganic Chemistry

CiteScore

2.80

自引率

10.30%

发文量

193

审稿时长

6 weeks

期刊介绍： Inorganics is an open access journal that covers all aspects of inorganic chemistry research. Topics include but are not limited to: synthesis and characterization of inorganic compounds, complexes and materials structure and bonding in inorganic molecular and solid state compounds spectroscopic, magnetic, physical and chemical properties of inorganic compounds chemical reactivity, physical properties and applications of inorganic compounds and materials mechanisms of inorganic reactions organometallic compounds inorganic cluster chemistry heterogenous and homogeneous catalytic reactions promoted by inorganic compounds thermodynamics and kinetics of significant new and known inorganic compounds supramolecular systems and coordination polymers bio-inorganic chemistry and applications of inorganic compounds in biological systems and medicine environmental and sustainable energy applications of inorganic compounds and materials MD