Dengue Fever in Pregnancy - Maternal and Fetal Outcome

Fatema Rahman, Dina Layla Hossain, Shikha Ganguly, F. N. Tawhida, Layla Khayrun Nahar
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Abstract

Background and objectives: There has been a lot of concern related to dengue infection in pregnant women in recent years due to an increase in number of dengue infections worldwide. Dengue fever during pregnancy is associated with early pregnancy failure, preterm delivery, low birth weight babies, prematurity, and occasionally neonatal mortalities. The primary objective is to find out the maternal and fetal outcome of pregnancy affected by Dengue fever. Materials and Method: This is a prospective observational study, conducted over a period of 3 months from 1st July to 30th September 2023 in Dhaka Medical College Hospital, Dhaka, Bangladesh. Result: Out of the 44 pregnant patients admitted with suspected dengue infection, 56.8% were diagnosed serologically positive by NS1 and 43.2% by Dengue IgM . Fever was found in 100% patients and Thrombocytopenia was found in 45.9% patients, PPH in 13.6%. Regarding obstetric management 25% got conservative management ,27.2% delivered vaginally and 38.6% undergone LSCS. About 25% pt needed to shift ICU in antenatal and postnatal period.4.5% were maternal mortality in this study period. On the other hand 13.7% were still born and 13.7% of the babies required NICU admission due to prematurity and low birth weight. Conclusion: Dengue related complications are high in pregnancy. Timely and precise interventions in dengue infected pregnant women are needed for optimal outcome. Early detection and access to proper medical care in this specific group by multidisciplinary team can reduce complications and mortality. J Bangladesh Coll Phys Surg 2023; 41: 21-24
妊娠期登革热--母体和胎儿的结局
背景和目的:近年来,由于全球登革热感染病例的增加,孕妇感染登革热的问题备受关注。妊娠期登革热与早期妊娠失败、早产、低出生体重儿、早产以及偶尔的新生儿死亡有关。本研究的主要目的是了解受登革热影响的孕妇和胎儿的妊娠结局。材料和方法:这是一项前瞻性观察研究,于 2023 年 7 月 1 日至 9 月 30 日在孟加拉国达卡的达卡医学院附属医院进行,为期 3 个月。研究结果在入院的 44 名疑似登革热感染孕妇中,56.8% 被诊断为 NS1 血清学阳性,43.2% 被诊断为登革热 IgM 阳性。100%的患者出现发热,45.9%的患者出现血小板减少,13.6%的患者出现 PPH。在产科治疗方面,25%的患者接受了保守治疗,27.2%的患者经阴道分娩,38.6%的患者接受了 LSCS。约 25% 的产妇在产前和产后需要转入重症监护室。另一方面,13.7%的婴儿为死产,13.7%的婴儿因早产和出生体重不足而需要入住新生儿重症监护室。结论妊娠期登革热相关并发症的发病率很高。需要对感染登革热的孕妇进行及时、准确的干预,以获得最佳治疗效果。由多学科团队对这一特殊群体进行早期检测并提供适当的医疗护理,可以减少并发症和死亡率。J Bangladesh Coll Phys Surg 2023; 41: 21-24
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