The functional medicine significance of omega 6 to omega 3 ratio

Abstract

Omega-6 fatty acids and omega-3 fatty acids are essential fatty acids, which should be consumed and supplemented for the functioning of our bodies. The absolute essential fatty acids are linolenic acid and alpha-linolenic acid. However, considering the low conversion rate in vivo and their enzyme activity depending on individual genotype and disease condition, direct intake of gamma-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid is important. Requirements for essential fatty acids may vary from person to person. This means that the omega-6 and omega-3 fatty acid pathways compete to use the same enzymes, the modern Western diet focuses on omega-6 fats, and stress, aging, menopause, and relative deficiencies cause increased inflammation and decreased enzyme activity. The important thing is to consume or supplement fatty acids in a balanced manner rather than supplementing just one kind of 'healthy' fatty acid. Fatty acid imbalance is not a single problem but is complex and organically intertwined, so it usually causes complex problems. Excessive supplementation of one fatty acid can worsen the deficiency of other fatty acids, so wisdom is needed to supplement by checking blood omega-3 index and clinical evidence that can provide appropriate evidence.