Directions for optimizing the organization of long-term anticoagulant treatment

Natalia Sumarga, Adrian Belii
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Abstract

Background: In this study the organization of long-term anticoagulant treatment has been evaluated to estimate whether clinical practice is in accordance with current recommendations for optimal use and effective control of oral anticoagulant (OAC) treatment. Material and methods: Mixed (quantitative and qualitative), transversal, descriptive, selective study. Samples: quantitative study – 394 adult patients, eligible for anticoagulant treatment; qualitative study – 39 family doctors. Results: The rate of use of OAC treatment is 68%. The period from the diagnosis of the disease to the initiation of OAC treatment lasted one month or more in 59.1% of patients. 60.6% of patients do not have sufficient knowledge regarding the treatment of OAC. The high price is the most important barrier to direct oral anticoagulant administration (91.1%). Patients’ satisfaction with OAC treatment control is low, mainly for vitamin K antagonists (59.8%). 75.5% of respondents claim that OAC treatment control and management is poor. 40.3% do not perform safe therapeutic International Normalized Ratio control, and 54.7% are not in the optimal therapeutic range. Conclusions: The main barriers to adherence to OAC treatment: the burden of regular monitoring of blood parameters, perceived concern about complications, limited access to laboratory tests and specialist doctors, insufficient information about anticoagulation, and deficiencies in communication with medical staff. There is limited conviction, and uncertainty persists in the initiation and monitoring of OAC treatment by family doctors.
优化长期抗凝治疗组织的方向
背景:本研究评估了长期抗凝治疗的组织情况,以估计临床实践是否符合当前关于优化使用和有效控制口服抗凝剂(OAC)治疗的建议。材料和方法:混合(定量和定性)、横向、描述性、选择性研究。样本:定量研究--394 名符合抗凝治疗条件的成年患者;定性研究--39 名家庭医生。研究结果使用 OAC 治疗的比例为 68%。59.1%的患者从确诊疾病到开始接受 OAC 治疗的时间为一个月或更长。60.6%的患者对 OAC 治疗缺乏足够的了解。高昂的价格是直接使用口服抗凝剂的最主要障碍(91.1%)。患者对 OAC 治疗控制的满意度较低,主要是对维生素 K 拮抗剂的满意度(59.8%)。75.5%的受访者称 OAC 治疗控制和管理不佳。40.3%的受访者没有进行安全的治疗性国际正常化比率控制,54.7%的受访者没有达到最佳治疗范围。结论:坚持 OAC 治疗的主要障碍:定期监测血液参数的负担、对并发症的担忧、获得实验室检测和专科医生服务的机会有限、抗凝信息不足以及与医务人员沟通不畅。家庭医生在启动和监测 OAC 治疗方面的信念有限,不确定性持续存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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