Prevalence and Risk Factors of Helicobacter Pylori Infection among Patients with Peptic Ulcer Disease Attendeing Muhammad Abdullahi Wase Teaching Hospital

Sani A Haruna
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Abstract

Duodenal (DU) and gastric (GU) ulcers are both included in the category of peptic ulcer disease (PUD). The first section of the duodenum or the stomach's pre-pyloric region (antrum) are the most common sites for duodenal ulcers. Most cases of gastric ulcers occur in the stomach's lesser curvature, which connects to the body's antrum (angularis). The purpose of the study is to ascertain the prevalence and risk factors of Helicobacter pylori infections in Muhammad Abdullahi Wase Teaching Hospital patients suffering from peptic ulcer disease. Patients with PUD who had an H. pylori infection test performed between September and November 2019 at the Muhammad Abdullahi Wase Teaching Hospital in Kano, Nigeria, were included in the study. The One-step ANTI-HP in whole blood Rapid Screen Test was used to determine whether blood samples contained H. pylori infection. Seventy PUD patients had an overall prevalence rate of 80% for H. pylori infection; however, the percentage was higher in men (64.3%) than in women (35.7%). Patients with a house population of more than six (70%), those who drank pipe water (51.4%), those who took antiulcer drugs (67.1%), and those with a family history of PUD (55.7%) were the most common groups of patients with H. pylori infection. In conclusion, the age group with a male majority (31–50 years old) had the highest frequency of H. pylori infection. The main risk factors for H. pylori were using antiulcer drugs, drinking water in a particular way, and having a family history of PUD.
Muhammad Abdullahi Wase 教学医院消化性溃疡患者幽门螺杆菌感染的流行率和风险因素
十二指肠(DU)溃疡和胃(GU)溃疡都属于消化性溃疡病(PUD)的范畴。十二指肠溃疡最常见的发病部位是十二指肠的第一段或胃的幽门前区(窦部)。大多数胃溃疡发生在胃的小弯部,它与人体的窦部(angularis)相连。这项研究的目的是确定幽门螺杆菌感染在穆罕默德-阿卜杜拉希-瓦塞教学医院消化性溃疡病患者中的流行率和风险因素。本研究纳入了2019年9月至11月期间在尼日利亚卡诺市穆罕默德-阿卜杜拉希-瓦塞教学医院进行幽门螺杆菌感染检测的消化性溃疡患者。一步式全血ANTI-HP快速筛查试验用于确定血液样本中是否含有幽门螺杆菌感染。70 名 PUD 患者的幽门螺杆菌感染率为 80%,但男性(64.3%)高于女性(35.7%)。居住人口超过 6 人(70%)、饮用自来水(51.4%)、服用抗溃疡药物(67.1%)和有 PUD 家族史(55.7%)的患者是幽门螺杆菌感染的最常见人群。总之,男性占多数的年龄组(31-50 岁)感染幽门螺杆菌的频率最高。幽门螺杆菌感染的主要风险因素是使用抗溃疡药物、以特殊方式饮水以及有 PUD 家族史。
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