The effectiveness of exercises in patients with thumb carpometacarpal osteoarthritis: a study protocol for a systematic review and meta-analysis

S. Karanasios, Dimitra Mertyri, Fotis Karydis
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Abstract

Background: The thumb carpometacarpal osteoarthritis (CMC-OA) is a common musculoskeletal condition of the hand causing increased pain and significant disability. Although different modes of exercises are usually prescribed during the management of the condition, the evidence for their effectiveness is sparse. The aim of this protocol is to investigate through a systematic review the effectiveness of exercises compared with other non-surgical interventions in reducing pain and improving function in the management of the thumb CMC-OA. Methods: We will conduct this systematic review following the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. PubMed, CINAHL, EMBASE, PEDro, ScienceDirect, Cochrane Library, Grey literature databases and clinical trial registries will be searched. Two reviewers will independently evaluate the retrieved results. Subsequently, data extraction of the eligible trials will be conducted by two independent researchers. We will use the grading of recommendations assessment, development, and evaluation (GRADE) approach to assess the certainty of evidence. Conclusions: This systematic review will provide evidence for the clinical benefits of exercises compared with other conservative interventions in the management of patients with thumb CMC-OA. Trial registration: PROSPERO registration number is CRD42023461505.
锻炼对拇指腕掌骨关节炎患者的疗效:系统综述和荟萃分析的研究方案
背景:拇指腕掌骨关节炎(CMC-OA)是一种常见的手部肌肉骨骼疾病,会导致疼痛加剧和严重残疾。虽然在治疗过程中通常会开出不同的运动处方,但其有效性的证据却很少。本方案旨在通过系统性综述,研究在治疗拇指 CMC-OA 时,运动与其他非手术干预措施相比,在减轻疼痛和改善功能方面的有效性。方法:我们将按照系统性综述和荟萃分析(PRISMA)指南的首选报告项目进行此次系统性综述。我们将检索 PubMed、CINAHL、EMBASE、PEDro、ScienceDirect、Cochrane 图书馆、灰色文献数据库和临床试验登记处。两名审稿人将独立评估检索结果。随后,两名独立研究人员将对符合条件的试验进行数据提取。我们将采用建议评估、发展和评价分级法(GRADE)来评估证据的确定性。结论:本系统综述将提供证据,证明在治疗拇指 CMC-OA 患者时,运动与其他保守干预措施相比具有临床益处。试验注册:PROSPERO 注册号为 CRD42023461505。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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