PERSPECTIVES ON MALE AGING AND THERAPEUTIC IMPLICATIONS

Abstract

This article provides an in-depth analysis of the molecular and cellular alterations linked to the aging process in males. It elucidates the physiological disruptions that give rise to different diseases and a decrease in functional ability. The inquiry explores the complex correlation between aging, sexual dysfunction, and infertility in males, with a focus on the physiological alterations in spermatogonial stem cells and the impact of oxidative stress on male reproductive capacity. The function of testosterone replacement therapy and its potential advantages in enhancing sexual activity, bone density, and overall health in older males are highlighted. Nevertheless, it is prudent to exercise caution as there is a correlation between testosterone replacement therapy and heightened cardiovascular risk. The article summarizes rehabilitation options for elderly men, specifically focusing on exercise regimens and cardiac rehabilitation, as means to tackle erectile dysfunction and mitigate mortality risks. The advantages of yoga in enhancing mental and physical well-being in males, particularly those grappling with prostate cancer or infertility are mentioned. The significance of adopting a comprehensive and interdisciplinary strategy towards men's health is emphasized, with particular attention given to the contributions of primary care physicians, urologists, and nurses. The significance of customized communication tactics for males and the necessity of periodic examinations for promoting healthier aging are emphasized.