Risk of Depression according to Cumulative Exposure to a Low-Household Income Status in Individuals with Type 2 Diabetes Mellitus: A Nationwide Population- Based Study.

IF 6.8 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes & Metabolism Journal Pub Date : 2024-03-01 Epub Date: 2024-01-03 DOI:10.4093/dmj.2022.0299
So Hee Park, You-Bin Lee, Kyu-Na Lee, Bongsung Kim, So Hyun Cho, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
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Abstract

Backgruound: We aimed to identify the risk of incident depression according to cumulative exposure to a low-household income status in individuals with type 2 diabetes mellitus (T2DM).

Methods: For this retrospective longitudinal population-based cohort study, we used Korean National Health Insurance Service data from 2002 to 2018. Risk of depression was assessed according to cumulative exposure to low-household income status (defined as Medical Aid registration) during the previous 5 years among adults (aged ≥20 years) with T2DM and without baseline depression who underwent health examinations from 2009 to 2012 (n=2,027,317).

Results: During an average 6.23 years of follow-up, 401,175 incident depression cases occurred. Advance in cumulative number of years registered for medical aid during the previous 5 years from baseline was associated with an increased risk of depression in a dose-dependent manner (hazard ratio [HR], 1.44 [95% confidence interval (CI), 1.38 to 1.50]; HR, 1.40 [95% CI, 1.35 to 1.46]; HR, 1.42, [95% CI, 1.37 to 1.48]; HR, 1.46, [95% CI, 1.40 to 1.53]; HR, 1.69, [95% CI, 1.63 to 1.74] in groups with 1 to 5 exposed years, respectively). Insulin users exposed for 5 years to a low-household income state had the highest risk of depression among groups categorized by insulin use and duration of low-household income status.

Conclusion: Cumulative duration of low-household income status, defined as medical aid registration, was associated with an increased risk of depression in a dose-response manner in individuals with T2DM.

根据 2 型糖尿病患者累积暴露于低家庭收入状况的抑郁风险:一项基于全国人口的研究。
研究背景我们旨在根据2型糖尿病(T2DM)患者在低家庭收入状况下的累积暴露情况,确定其发生抑郁症的风险:在这项基于人群的回顾性纵向队列研究中,我们使用了2002年至2018年的韩国国民健康保险服务数据。根据2009年至2012年期间接受健康检查的T2DM成人(年龄≥20岁)中过去5年的低家庭收入状况(定义为医疗补助登记)累积暴露评估抑郁症风险(n=2,027,317):结果:在平均 6.23 年的随访期间,共有 401,175 例抑郁症病例。从基线算起,过去 5 年中累计医疗救助登记年数的增加与抑郁症风险的增加呈剂量依赖关系(危险比 [HR],1.44[95%置信区间(CI),1.38至1.50];暴露年限为1至5年的组别,HR,1.40[95%CI,1.35至1.46];HR,1.42,[95%CI,1.37至1.48];HR,1.46,[95%CI,1.40至1.53];HR,1.69,[95%CI,1.63至1.74])。在根据胰岛素使用情况和低家庭收入状态持续时间分类的群体中,胰岛素使用者在低家庭收入状态下暴露 5 年的抑郁风险最高:结论:在 T2DM 患者中,低家庭收入状态的累积持续时间(定义为医疗救助登记)与抑郁风险的增加呈剂量反应关系。
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来源期刊
Diabetes & Metabolism Journal
Diabetes & Metabolism Journal Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
10.40
自引率
6.80%
发文量
92
审稿时长
52 weeks
期刊介绍: The aims of the Diabetes & Metabolism Journal are to contribute to the cure of and education about diabetes mellitus, and the advancement of diabetology through the sharing of scientific information on the latest developments in diabetology among members of the Korean Diabetes Association and other international societies. The Journal publishes articles on basic and clinical studies, focusing on areas such as metabolism, epidemiology, pathogenesis, complications, and treatments relevant to diabetes mellitus. It also publishes articles covering obesity and cardiovascular disease. Articles on translational research and timely issues including ubiquitous care or new technology in the management of diabetes and metabolic disorders are welcome. In addition, genome research, meta-analysis, and randomized controlled studies are welcome for publication. The editorial board invites articles from international research or clinical study groups. Publication is determined by the editors and peer reviewers, who are experts in their specific fields of diabetology.
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